Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Repro > Women's health drugs > Flashcards

Women's health drugs Flashcards

1
Q

Methyldopa class

A

AntiHTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Methyldopa MOA

A

Central alpha-adrenergic inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Methyldopa indication

A

HTN in PG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Labetalol class

A

AntiHTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Labetalol MOA

A

A1/B1/B2 blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Labetalol indication

A

DOC for HTN in PG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Folic acid class

A

Water soluble VIT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Folic acid MOA

A

Required for formation of multiple co-enzymes in protein synthesis. Provides folate for DNA synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Folic acid indications

A

Prevention of neural tube defects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Folic acid contraindication

A

Untreated B12 deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pyridoxine class

A

VIT B6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Pyridoxine MOA

A

Inhibits CRTZ; decreases vestibular stimulation, decreases labrynth function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Pyridoxine indication

A

In combo with doxylamine (an antihistamine) for N/V in PG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Pyridoxine side effect

A

Sedating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pyridoxine contraindication

A

Narrow angle glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Magnesium Sulfate

A

Tocolytic agent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Mg++ sulfate MOA

A

Decreases Ach in motor nerve terminals
Slows rate of SAN impulse formation
Relaxes bronchial smooth muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Mg++ sulfate indications

A

Preterm labor/eclampsia
Torsades
Refractory pediatric status asthmaticus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

COCs…MOA

A

Suppression of FSH/LH with suppression of ovulation and implantation; thickening of cervical mucus; slowing of tubal motility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

COCs indication

A

Contraception…some have added benefit of regulating menses or mitigating menopausal sxs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

COC side effects: excess estrogen

A

bloating
migraines
decreased libido
wt gain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

COC side effects: deficient estrogen

A

spotting
amenorrhea
vaginal dryness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

COC side effects: excess progestin

A

acne
increased appetite
fatigue
hirsutism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

COC side effects: deficient progestin

A

amenorrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

COC absolute contraindications

A 
Hx of...
Thromboembolism
CVD/CAD
Breast CA
estrogen-dependent neoplasm
unDx'd uterine bleeding
PG
smoking >15 cigs/day and >35 y/o
migraines with aura
hepatic disease/tumor
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

COC relatice contraindications

A

Smoking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

COC Dx-Dx interactions

A 
Anticonvulsants
Benzos
Corticosteroids
PCNs
Protease inhibitors
Rifampin
St. John's wort
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What CYP subsrate is EE?

A

CYP3A4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Monophasic COC

A

Loestrin Fe 1/20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Biphasic COC

A

Lo Loestrin Fe

31
Q

Triphasic COC

A

Triphasil

32
Q

Quadraphasic COC

A

Natazia

33
Q

You have to take tri- and quadraphasic COCs at the same time every day to prevent…

A

breakthrough bleeding

34
Q

Triphasil is also indicated to treat…

A

menopausal sxs

35
Q

Progestin-only BCPs MOA

A

Prevents mid-cycle FSH/LH surge
inhibits ovulation and implantation
thickens cervical mucus
slows tubal transport

36
Q

Progestin only BCPs indication

A

Contraception - a good choice for women who can’t take COCs

37
Q

Pros of Progestin only BCPs

A

Less risk of blood clots

minimized menses after 6-9 cycles

38
Q

Cons of progestin only BCPs

A

More breakthrough bleeding

must take at the same time every day for efficacy

39
Q

Progestin-only BCP

A

Ovrette

40
Q

Extended cycle BCP

A

Lybrel

41
Q

Quadraphasic extended cycle BCP

A

Quartette

42
Q

In addition to contraception, Lybrel and Quartette are good for…

A

menstrual-related sxs

43
Q

Conjugated Equine estrogen

A

Estrogen suppliment

44
Q

CEE indications

A

moderate to severe vasomotor sxs, vaginal mucosal atrophy

45
Q

CEE contraindications

A

VTE, breast CA, stroke, PG, unDx uterine bleeding

46
Q

CEE Dx-Dx interactions

A

CYP3A4 inducers decr [CEE]

CYP3A4 inhibitors incr [CEE]

47
Q

CEE black box warning

A

CVA, dementia, malignancies, etc

48
Q

Depot MPA

A

Progestogen

49
Q

Depot MPA indication

A

Contraception - good for women who have a contraindication for EE

50
Q

How long can amenorrhea/infertility last after you D/C Depot?

A

12-18 months

51
Q

What is a potential consequence for continued, long term use of Depot?

A

Decreased BMD

52
Q

Mifepristone: class

A

Abortifactant

53
Q

Mifepristone: MOA

A

Inhibits progesterone receptors - antagonizing endometrium and myometrium

54
Q

Mifepristone: indication

A

Early PG terminiation

55
Q

Mifepristone: contraindications

A

Ectopic PG
IUD in place
bleeding d/o

56
Q

Mifepristone: black box warning

A

Bleeding and infection

57
Q

Ulipristal: class

A

Post exposure contraception

58
Q

Ulipristal MOA

A

Binds to progesterone receptors, inhibiting or delaying ovulation; alters endometrium

59
Q

Ulipristal indication

A

emergency contraception

60
Q

Ulipristal side effects

A

N/V

If vomiting occurs w/in first 3 hours, you may need to re-adminiater

61
Q

Can Ulipristal be given to women who can’t take COCs?

A

Yes

62
Q

Flibansterin: class

A

Mixed 5-HT1A agonist/5-HT2A antagonist

63
Q

Flibansterin MOA

A

Unknown

64
Q

Flibansterin indication

A

Hypoactive sexual desire d/o in premenopausal women

65
Q

Flibansterin side effects

A

CNS depression

HOTN/syncope

66
Q

Flibansterin contraindications

A

ethanol

liver dz

67
Q

How much does 30 days worth of Flibansterin cost

A

$960

68
Q

Osphema class

A

Selective estrogen receptor modulator

69
Q

Osphema MOA

A

Selective activation/inhibition of estrogen pathways in different tissues

70
Q

Osphema Indication

A

Dyspareunia secondary to vulvar/vaginal atrophy in post menopausal women

71
Q

Osphema side effects

A

Hyperydrosis, hot flashes, endometerial proliferation

72
Q

Osphema contraindications

A

Abnormal vaginal bleeding
DVT/PE/blood clots
Estrogen-dependent tumor
PG

73
Q

Osphema should be administered with…

A

food

74
Q

How much does 90 days worth of Osphema cost?

A

$600

Repro (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions