GU and Misc drugs

Question 1

Flomax class

Answer 1

Alpha 1 adrenergic antagonist

Question 2

Flomax MOA

Answer 2

Relaxed bladder neck, prostatic urethra, prostatic smooth muscle

Question 3

Flomax indication

Answer 3

Moderate to severe BPH

Question 4

Flomax side effects

Answer 4

Syncope, orthostatic HOTN

Question 5

If you’re on Flomax and you want to use a PDE5 inhibitor, how long do you have to wait?

Answer 5

4 hours

Question 6

Flomax onset of action

Answer 6

days to 2 weeks

Question 7

Proscar class

Answer 7

5a-reductase inhibitor

Question 8

Proscar MOA

Answer 8

Inhibits conversion of Testosterone to Dihydrotestosterone

Question 9

Proscar Indication

Answer 9

2nd line drug for BPH

Question 10

Proscar onset of action

Answer 10

up to 6 months

Question 11

Why do you need to avoid pregnant females while on Proscar?

Answer 11

Femination of male fetus

Question 12

Leupron class

Answer 12

Anti-androgen

Question 13

Leupron MOA

Answer 13

GnRH/LHRH agonist

Question 14

Leupron Indication

Answer 14

Palliative care in prostate CA, endometriosis

Question 15

Leupron side effects

Answer 15

increased lipids, fatigue, angina, dysrhythmias

Question 16

Eulexin class

Answer 16

Anti-androgen

Question 17

Eulexin MOA

Answer 17

Inhibits androgen binding at target tissues

Question 18

Eulexin indication

Answer 18

Metastatic prostate CA with LHRH agonist

Question 19

Eulexin side effects

Answer 19

gynecomastia, gallactorrhea, hot flashes, impotence

Question 20

Eulexin contraindicationd

Answer 20

liver disease, G6PD deficiency

Question 21

Testosterone class

Answer 21

Sex hormone

Question 22

Testosterone MOA

Answer 22

Replacement

Question 23

Testosterone indication

Answer 23

Hypogonadism

Question 24

Testosterone side effects

Answer 24

Prostate hypertophy
Emotional liability
Altered libido
Hepatitis
DVT
Aggression
HTN
Acne

Question 25

Testosterone contraindications

Answer 25

Hepatic/renal/cardiac disease

Question 26

What can happen to female sex partners if you're on Testosterone?

Answer 26

Virilization

Question 27

Tofranil class

Answer 27

Tricyclic antidepressant

Question 28

Tofranil MOA

Answer 28

Increases synaptic [serotonin, norepi]; down-regulated B-adrenergic receptors; anticholinergic

Question 29

Tofranil indications

Answer 29

Depression | Anticholinergic effect may impact urinary incontinence

Question 30

Tofranil side effects

Answer 30

``` Sedation EKG changes CHF orthostastis anticholinergic effects ```

Question 31

Detrol LA class

Answer 31

m3 antimuscarinic

Question 32

Detrol LA MOA

Answer 32

Selective antagonist against bladder muscarininc receptors; decrease detrussor muscle pressure; increase residual bladder volume

Question 33

Detrol LA indication

Answer 33

Urge incontinence

Question 34

Detrol LA side effects

Answer 34

dry mouth headache long QT arthralgia

Question 35

Detrol LA contraindications

Answer 35

urinary retention gastric retention closed angle glaucoma

Question 36

Detrol LA Dx-Dx interactions

Answer 36

CYP3A4 substrates

Question 37

Ditropan LA class

Answer 37

m3 antimuscarininc

Question 38

Ditropan LA indication

Answer 38

urge incontinence

Question 39

Ditropan LA Dx-Dx interactions

Answer 39

Other anticholinergics

Question 40

Viagra (Sildenafil) class

Answer 40

PDE5 inhibitor

Question 41

Viagra MOA

Answer 41

Inhibits PDE5 to increase NO, leading to corpus cavernosum relaxation

Question 42

Viagra indication

Answer 42

Erectile dysfunction | pulm HTN

Question 43

Viagra side effects

Answer 43

``` H/A dyspepsia color vision changes HOTN angina ```

Question 44

Viagra contraindications

Answer 44

``` Nitrates CVD unstable angina HTN >170/110 HOTN ```

Question 45

Viagra Dx-Dx interactions

Answer 45

Nitrates CYP3A4 substrates grapefruit juice

Question 46

Viagra t 1/2

Answer 46

4 hours

Question 47

Cialis (Tadalafil) class

Answer 47

PDE5 inhibitor

Question 48

Cialis indication

Answer 48

Erectile dysfunction | pulm HTN

Question 49

Cialis dosing

Answer 49

PRN | or 2.5 mg daily

Question 50

Mirabegron class

Answer 50

Beta 3 agonist

Question 51

Mirabegron MOA

Answer 51

Activates B3 adrenergic receptors in the bladder, relaxing the detrussor muscle during the urine storage phase

Question 52

Mirabegron indication

Answer 52

Urge incontinence

Question 53

Mirabegron side effects

Answer 53

HTN tachycardia UTI

Question 54

Mirabegron contraindications

Answer 54

``` Stage 5 kidney disease Liver disease pregnancy uncontrolled HTN bladder outlet obstruction ```

Question 55

How much does 90 days of Mirabegron cost?

Answer 55

$980.00