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Repro > GU and Misc drugs > Flashcards

GU and Misc drugs Flashcards

1
Q

Flomax class

A

Alpha 1 adrenergic antagonist

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2
Q

Flomax MOA

A

Relaxed bladder neck, prostatic urethra, prostatic smooth muscle

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3
Q

Flomax indication

A

Moderate to severe BPH

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4
Q

Flomax side effects

A

Syncope, orthostatic HOTN

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5
Q

If you’re on Flomax and you want to use a PDE5 inhibitor, how long do you have to wait?

A

4 hours

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6
Q

Flomax onset of action

A

days to 2 weeks

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7
Q

Proscar class

A

5a-reductase inhibitor

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8
Q

Proscar MOA

A

Inhibits conversion of Testosterone to Dihydrotestosterone

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9
Q

Proscar Indication

A

2nd line drug for BPH

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10
Q

Proscar onset of action

A

up to 6 months

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11
Q

Why do you need to avoid pregnant females while on Proscar?

A

Femination of male fetus

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12
Q

Leupron class

A

Anti-androgen

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13
Q

Leupron MOA

A

GnRH/LHRH agonist

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14
Q

Leupron Indication

A

Palliative care in prostate CA, endometriosis

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15
Q

Leupron side effects

A

increased lipids, fatigue, angina, dysrhythmias

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16
Q

Eulexin class

A

Anti-androgen

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17
Q

Eulexin MOA

A

Inhibits androgen binding at target tissues

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18
Q

Eulexin indication

A

Metastatic prostate CA with LHRH agonist

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19
Q

Eulexin side effects

A

gynecomastia, gallactorrhea, hot flashes, impotence

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20
Q

Eulexin contraindicationd

A

liver disease, G6PD deficiency

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21
Q

Testosterone class

A

Sex hormone

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22
Q

Testosterone MOA

A

Replacement

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23
Q

Testosterone indication

A

Hypogonadism

24
Q

Testosterone side effects

A 
Prostate hypertophy
Emotional liability
Altered libido
Hepatitis
DVT
Aggression
HTN
Acne
25
Q

Testosterone contraindications

A

Hepatic/renal/cardiac disease

26
Q

What can happen to female sex partners if you’re on Testosterone?

A

Virilization

27
Q

Tofranil class

A

Tricyclic antidepressant

28
Q

Tofranil MOA

A

Increases synaptic [serotonin, norepi]; down-regulated B-adrenergic receptors; anticholinergic

29
Q

Tofranil indications

A

Depression

Anticholinergic effect may impact urinary incontinence

30
Q

Tofranil side effects

A 
Sedation
EKG changes
 CHF
orthostastis
anticholinergic effects
31
Q

Detrol LA class

A

m3 antimuscarinic

32
Q

Detrol LA MOA

A

Selective antagonist against bladder muscarininc receptors; decrease detrussor muscle pressure; increase residual bladder volume

33
Q

Detrol LA indication

A

Urge incontinence

34
Q

Detrol LA side effects

A

dry mouth
headache
long QT
arthralgia

35
Q

Detrol LA contraindications

A

urinary retention
gastric retention
closed angle glaucoma

36
Q

Detrol LA Dx-Dx interactions

A

CYP3A4 substrates

37
Q

Ditropan LA class

A

m3 antimuscarininc

38
Q

Ditropan LA indication

A

urge incontinence

39
Q

Ditropan LA Dx-Dx interactions

A

Other anticholinergics

40
Q

Viagra (Sildenafil) class

A

PDE5 inhibitor

41
Q

Viagra MOA

A

Inhibits PDE5 to increase NO, leading to corpus cavernosum relaxation

42
Q

Viagra indication

A

Erectile dysfunction

pulm HTN

43
Q

Viagra side effects

A 
H/A
dyspepsia
color vision changes
HOTN
angina
44
Q

Viagra contraindications

A 
Nitrates
CVD
unstable angina
HTN >170/110
HOTN
45
Q

Viagra Dx-Dx interactions

A

Nitrates
CYP3A4 substrates
grapefruit juice

46
Q

Viagra t 1/2

A

4 hours

47
Q

Cialis (Tadalafil) class

A

PDE5 inhibitor

48
Q

Cialis indication

A

Erectile dysfunction

pulm HTN

49
Q

Cialis dosing

A

PRN

or 2.5 mg daily

50
Q

Mirabegron class

A

Beta 3 agonist

51
Q

Mirabegron MOA

A

Activates B3 adrenergic receptors in the bladder, relaxing the detrussor muscle during the urine storage phase

52
Q

Mirabegron indication

A

Urge incontinence

53
Q

Mirabegron side effects

A

HTN
tachycardia
UTI

54
Q

Mirabegron contraindications

A 
Stage 5 kidney disease
Liver disease
pregnancy
uncontrolled HTN
bladder outlet obstruction
55
Q

How much does 90 days of Mirabegron cost?

A

$980.00

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