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Repro > Repro Abx > Flashcards

Repro Abx Flashcards

1
Q

Metronidazole MOA

A

Inhibits protein synthesis when chemical structure is reduced

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2
Q

Metronidazole indication

A

Trichomoniasis

Bacterial vaginosis

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3
Q

Metronidazole side effects

A

flat T waves
aseptic meningitis
metallic taste

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4
Q

Metronidazole contraindications

A

Blood dyscrasia
CHF
liver dz
seizure Hx

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5
Q

Metronidazole Dx-Dx interactions

A

ETOH (disulfram rxn)

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6
Q

Ceftriaxone MOA

A

Binds to PBP and interferes with transpeptidation of bacterial cell wall

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7
Q

Ceftriaxone indication

A

Gonorrhea

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8
Q

Ceftriaxone side effects

A

rash
diarrhea
super infections
seizures

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9
Q

Ceftriaxone contraindication

A

PCN anaphylaxis

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10
Q

How is Ceftriaxone cleared

A

Primarily through biliary duct

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11
Q

Azythromycin MOA

A

Interferes with 50s bacterial ribosomal production

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12
Q

Azythromycin indication

A

Chlamydia, PID, PCN substitute

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13
Q

Azythromycin side effect

A

long QT

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14
Q

Benzathine PCN G indication

A

Syphilis

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15
Q

Nitrofurantoin MOA

A

inhibits several bacterial enzyme systems, interfering with metabolism and possible cell wall synthesis

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16
Q

Nitrofurantoin indication

A

UTI

17
Q

Nitrofurantoin side effects

A

angioedema
C-diff
brown urine
pulmonary fibrosis

18
Q

Nitrofurantoin contraindication

A

G6PD deficiency

GFR

19
Q

Nitrofurantoin can give you a false positive…

A

urine glucose

20
Q

Doxycycline MOA

A

Interferes with 30s bacterial ribosomal production

21
Q

Doxycycline indication

A

syphilis

22
Q

Doxycycline PG category

A

D

23
Q

Doxycycline side effects

A

N/V/D, photosensitivity, yeast infection

24
Q

Truvada class

A

Antiretroviral

25
Q

Truvada MOA

A

Interferes with DNA polymerase function, resulting in viral inhibition

26
Q

Truvada indication

A

HIV1

PrEP

27
Q

What must be dispensed with each Rx?

A

FDA approved med guide

28
Q

How much does 30 tabs of Truvada cost?

A

$1149

29
Q

Truvada black box warning

A

lactic acidosis

30
Q

Valcyclovir MOA

A

Inhibits viral DNA synthesis & replication

31
Q

Clotrimazole cream: class

A

Antifungal

32
Q

Clotrimazole cream MOA

A

Alters fungal cell wall permeability

33
Q

Clotrimazole cream indication

A

Candidiasis

Repro (3 decks)

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