Women/Men Health Meds Flashcards
Conjugated Estrogens
premarin
Conjugated Estrogens Uses
treatment of moderate-severe vasomotor sx (hot flashes) of menopause
GU sx including atrophic vaginitis, vulvar atrophy or dyspareunia whether menopause is natural or surgical
Conjugated Estrogens SE
nausea
HA
breast tenderness
Conjugated Estrogens ADE
thromboembolism
thrombophlebitis
PE
MI
CVA
HTN
ovarian cancer
if still has uterus; endometrial hyperplasia, endometrial cancer
Conjugated Estrogens Nursing Interventions
CI in pts with history of stroke, thrombophlebitis, thromboembolism, thromboembolic disease or MI
increased risk of stroke and DVT
monitor for any signs of MI, CVA, DVT or HTN; breakthrough bleeding
give oral forms with food to decrease nausea
smoking cessation is critical!!
encourage non pharmacological strategies to decrease sx of menopause like exercise
ensure annual mammography and BSE
typically used no longer than 3-5 yrs (usually not recommended for women 60+)
multiple drug interactions
Testosterone Uses and Administration
bind to androgen receptors to control development and maintenance of sexual processes, accessory sexual organs, cell metabolism and bone/muscle growth
used for androgen deficiency, hypogonadism, replacement therapy for testicular failure, delayed puberty in teens
nasal, implant, transdermal, parenteral
Testosterone SE
priapism
gynecomastia
urinary urgency
GI distress
insomnia
increased salivation
alterations in sexual desire
lethargy
hyper Ca
stops spermatogenesis
increases cholesterol
alters thyroid/liver function
Testosterone Nursing Interventions
teach good handwashing to prevent accidental exposure to gels/topical agents
if used in women, may expect virilization and should decrease once continued
premature epiphyseal closure may occur if given in children who haven’t received full height
may cause edema and weight gain
men should be screened for prostate cancer prior to starting
PDE5 Inhibitor
sildenafil (Viagra)
PDE5 Inhibitor Uses
ED (off label for pulmonary HTN and Raynauds)
PDE5 Inhibitor SE
HA
flushing
n/d
dizziness
dyspepsia
stuffy/runny nose
PDE5 Inhibitor ADE
anaphylaxis
angioedema
angina
AV block
V tach
cardiac arrest
seizures
PDE5 Inhibitor Nursing Interventions
tell provider if any history of bleeding problems or high/low BP, heart disease or priapism
don’t drive or use heavy machinery if experiencing drowsiness or dizziness
teach pts to take with full glass of water; one hour before sex
don’t take with nitrate meds; use caution with antihypertensives
Biophosphonates
alendronate (Fosamax)
Biophosphonates Uses
used for postmenopausal osteoporosis
osteoporosis in men
corticosteroid induced osteoporosis in women
Biophosphonates SE
GI upset (n/d, dyspepsia, abd pain, flatulence, GERD)
MSK pain
Biophosphonates ADE
esophageal/peptic ulceration
angioedema
bone fractures in long term use
osteonecrosis of jaw
Biophosphonates Nursing Interventions
pt must be able to sit up or stand at least 30 min after first dose
must be given with full glass of water ONLY
don’t take if any problems with sitting, standing or swallowing
call provider if any severe jaw, muscle, bone or joint pain
inform dentist that youre on this med because it affects healing and increases risk of infection
Anti-Androgens
finasteride (Propecia)
Anti-Androgens Uses
BPH (reduces sx of urinary retention and male pattern hair loss where treatment may be lifelong)
Anti-Androgens SE
decreased libido
decreased ejaculate volume
breast enlargement
Anti-Androgens ADE
depression
malignancy
reduced PSA (monitor!!)
Anti-Androgens Nursing Interventions
monitor symptoms of BPH
notify pts that it may take 4-6 months to notice full effects
newer drugs have less SE
report HA if not relieved by OTC meds
report severe dizziness or fainting
ensure that women don’t handle finasteride, especially if crushed due to risk of transdermal absorption
