woah Flashcards

hit the woah

1
Q

METABOLITE

parathion

A

paraoxon

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2
Q

METABOLITE

imipramine

A

desipramine

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3
Q

METABOLITE

malathion

A

malaoxon

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4
Q

METABOLITE

methamphetamine

A

p-hydroxyl amphetamine

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5
Q

METABOLITE

paracetamol

A

N-acetyl-para-quinoneimine

NAPQI

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6
Q

METABOLITE

diquat/paraquat

A

free radicals, reactive O2 species

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7
Q

METABOLITE

ethylene glycol

A

oxalic acid

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8
Q

METABOLITE

aspirin

A

salicylic acid

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8
Q

METABOLITE

allopurinol

A

alloxanthine

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9
Q

METABOLITE

chloramphenicol

A

glycolic acid metabolite

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9
Q

METABOLITE

amitriptyline

A

alloxanthine

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9
Q

METABOLITE

codeine

A

morphine

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10
Q

METABOLITE

cortisone

A

cortisol

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11
Q

METABOLITE

acetohexamide

A

hydroxyhexamide

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12
Q

METABOLITE

phenylbutazone

A

oxyphenylbutazone

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13
Q

METABOLITE

primidone

A

phenobarbital

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14
Q

METABOLITE

diazepam

A

desmethyldiazepam, oxazepam

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15
Q

METABOLITE

digitoxin

A

digoxin

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16
Q

METABOLITE

quinidine

A

3-hydroxyquinidine

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17
Q

METABOLITE

theophylline

A

caffeine

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18
Q

METABOLITE

acetonitrile

A

cyanide

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19
Q

METABOLITE

aromatic HCl

A

expoxides

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20
Q

METABOLITE

ethanol

A

acetaldehyde

21
Q

METABOLITE

isopropyl alcohol

A

acetone

22
Q

METABOLITE

methylene oxide

A

carbon monoxide

23
Q

METABOLITE

methanol

A

formaldehyde, formic acid

24
Q

METABOLITE

naphthalene

A

epoxide

25
Q

METABOLITE

chloral hydrate

A

trichloroethanol

26
Q

METABOLITE

prednisone

A

prednisolone

27
Q

METABOLITE

benzyl alcohol

A

benzoic acid, hippuric acid

28
Q

METABOLITE

meperidine

A

normeperidine

29
Q

ZOOTOXINS

produces cholinergic signs & symptoms, flushed sweating face contorted in a painful grimace with conjunctivitis, restlessness & HPN

tx: calcium gluconate, antivenom

A

latrotoxin

from black widow/hourglass spider (Latrodectus mactans)

30
Q

ZOOTOXIN

a neurotoxin

tx: barbiturate & IV antivenom

A

5-hydroxytryptamine

from scorpion (Centuroides sculpturatus)

31
Q

ZOOTOXIN

  • causes anaphylactic reaction
  • (formic acid from red ants)

tx: diphenhydramine & steroids

A

bee venom

from hymenoptera (bee, wasps, ants)

32
Q

ZOOTOXINS

  • first aid: suction & tourniquet, incision (w/in 20 mins to remove 20%)

tx: antivenom

A

hyaluronidase

from snakes

33
Q

ZOOTOXINS

tx: barbiturates, diazepam (convulsions), calcium gluconate, propranolol

A

tetrodotoxin

from amphibians [toads, newts, frogs (bufotoxin), puffer fishes]

34
Q

ZOOTOXINS

  • local irritants
  • aphrodisiac
A

cantharidin

from blister fly, spanish fly

35
Q

ZOOTOXINS

  • sharp metallic taste
  • abdominal pain
  • vomiting
  • diarrhea
A

clupeotoxin

from oysters, sardines (venerupin), anchovies

36
Q

ZOOTOXINS

  • confused with MSG reactions
  • may be caused by dolphin
A

scromboid toxin

from tuna (saurine), mackerel (gemblid) –> dolphin is non-scromboid

37
Q

ZOOTOXIN

most common poison from ingested fish

A

ciguatoxin

from fish organs (liver)

38
Q

ANTIDOTES – AGRICULTURAL POISONS

organophosphate

A

atropine, pralidoxime

39
Q

ANTIDOTES – AGRICULTURAL POISONS

carbamate insecticide

A

atropine

40
Q

ANTIDOTES – AGRICULTURAL POISONS

hydrocarbon insecticide

A

physostigmine

41
Q

ANTIDOTES – AGRICULTURAL POISONS

parathion

A

pralidoxime

42
Q

ANTIDOTES – AGRICULTURAL POISONS

paraquat

A
  • bentonite
  • fuller’s earth
  • sodium sulfate (Na2SO4)
43
Q

ANTIDOTES – AGRICULTURAL POISONS

barium

A
  • magnesium sulfate (MgSO4)
  • benzodiazepines
44
Q

ANTIDOTES – AGRICULTURAL POISONS

DDT

dichloro-diphenyl-trichloroethane

A

barbiturate

45
Q

ANTIDOTES – AGRICULTURAL POISONS

aniline, nitrobenzene

A

methylene blue

46
Q

ANTIDOTES – ALCOHOLS, GLYCOLS

methanol

A
  • ethanol
  • fomepizole
  • morphine
  • vit b9
47
Q

ANTIDOTES – ALCOHOLS, GLYCOLS

ethanol

A

disulfiram

48
Q

ANTIDOTES – ALCOHOLS, GLYCOLS

ethylene glycol

A
  • ethanol
  • fomepizole
  • vit b9
49
Q

ANTIDOTES – ALDEHYDE

formaldehyde

A
  • ammonia
  • sodium bicarbonate (NaHCO3)
50
Q

ANTIDOTES – ALDEHYDE

kerosene

A

mineral oil

51
Q

ANTIDOTES – CORROSIVES

  • oxalic acid
  • sodium phosphate
  • fluoride
A

calcium gluconate

52
Q

ANTIDOTES – CORROSIVES

ammonia

A

formaldehyde

53
Q

ANTIDOTES – CORROSIVES

bromine

A
  • sodium chloride
  • ammonium chloride (NH4Cl)