WK3- Wound Etiology Part 2 Flashcards
Define diabetes mellitus
the body’s inability to produce or use inuslin appropriately
What are the different forms of diabetes mellitus ?
Typ1A: immune mediated destruction of beta cells of pancreas, called insulin dependent DM, IDDM
Type1B: idiopathic DM due to heredity
Type2: insulin resistance, people normally overweight, impaired insulin secretion.
What is an A1C level and what are the normal, pre-diabetic ranges and diabetic ranges ?
A1C is the average blood glucose over 3 months
HgB A1C levels:
Normal: <5.7%, <100mg/dl glucose
Pre-Diabetes: 5.7-6.4, 100-125 mg/dl
Diabetes: > or equal to 6.5%, 125 mg/dl
What are the common and general damage tissue damage theories of DM ?
- changes RBCs, platelets, capillaries
- alters blood flow
- increases microvascular pressure
glycosylated proteins cause trauma, sorbitol accumulation as a result of glucose breakdown damages tissues.
What is DM neuropathy and what are its causes ?
neuropathy is degradation of motor, sensory, and or autonomic innervation to distal appendages
theorized to be due to segmental demyelination of nervous cells, or blood being starved from nervous tissue
What is diabetic neuropathic osteoarthropathy ?
inflammatory phase characterized by foot edema, erythema, and increased temp
bone and articular destruction ensue, progressing to dislocation and fracture
two theories for cause:
neurovascular theory and neurotraumatic theory
What kind of foot deformities can a PT expect to see in those with DM ?
impaired ROM: ankle and great toe
other foot deformities such as pes equinus, hallux valgus
charcot foot: midfoot collapse at tarsal metatarsal junction.
What are the general characteristics of neuropathic ulcers ?
typically no pain due to paresthesia
usually on plantar aspect of foot
round, punched out, minimal drainage
dry, cracked skin, callus, foot structural deformities
normal or accentuated pulses to atherosclerosis
normal or increased temp
Describe the different grades of the wagner scale
0- no open lesions; may have deformity or cellulitis
1- superficial ulcer
2- deep ulcer to tendon, capsule or bone
3- deep ulcer with abscess, osteolyelitis, or joint sepsis
4- localized gangrene
5- gangrene of entire foot
What are the indications for physician referral in patients with neuropathic ulcers ?
ABI less than .8, delayed capillary refill, abnormal doppler studies
What is the average healing time for neuropathic ulcers ?
12-14 weeks
What are the contraindications to a total contact cast ?
osteomyelitis, gangrene, fluctuating edema, active infection, ABI <.45
True or False. Step to gait patterns are ineffective at decreasing plantar pressure
false
When should you refer a patient with a neuropathic ulcer ?
ABI <.8
Failure to respond to treatment
Suspect infection
exposed bone or capsule
What is the difference between primary and secondary lymphedema ?
primary: congenital malformation or impaired lymphatics
secondary: acquired lymphatic disorder