WK14: Transfusion Medicine Flashcards
multidisciplinary branch of medicine that is concerned with the transfusion of blood components, including proper selection and utilization of blood components as well as removal of blood or blood components in the treatment or prevention of disease
Transfusion Medicine
Transfer of blood or blood components from one person into another person
Blood Transfusion
blood less than 24hrs old from the time of collection
Fresh Blood Transfusion
Blood collected from a patient for re-transfusion at a later time into the same individual
Autologous transfusion
Repeated transfusion of blood over a long period of time
Multiple Transfusion
Number of units transfused in a 24hrs period exceeds the recipient’s blood volume
Massive Transfusion
treatment for Hemorrhage due to thrombocytopenia
PLT concentrated
treatment for Hemorrhage due to coagulopathy
FFP, cryoprecipitate
Bone marrow transplant patients are at risk for ________
TA-GVHD
The final clerical check is performed at the _________
patient bed side by the nurse
True or False
Blood components are infused slowly for the first 5-10 mins while the patient is closely
observed for signs of a transfusion reactions
False (10-15)
Why is blood warming required in rapid transfusion and exchange transfusions?
cold blood can cause hypothermia
assess the effectives of the transfusion of
platelets
Corrected Count Increment
RDP good increment
> 10,000/uL
RDP refractoriness
<5000/uL
defined as the failure to yield an increase in recipient’s platelet count on transfusion of suitably preserved platelets
PLT refractoriness
MCC of PLT refractoriness
HLA alloimmunization
result from prior exposure to donor blood components.
HLA alloimmunization
Patient who are unresponsive to random donor platelet due to HLA alloimmunization or to limit exposure from multiple donors
Single donor PLT
SDP good increment
60,000/uL
SDP refractoriness
<20,000/uL
Used for Multiple clotting factor deficiencies especially the labile factors
FFP
Treatment of patients with von Willebrand’s disease, Hemophilia A (factor VII deficiency), or hypofibrinogenemia
Cryoprecipitate Anti-Hemophilic factor