wk10- skin and musculoskeletal infections Flashcards
(33 cards)
immunological portal of entries include
microbial antigens
toxins
PAMPS
diagnosis of skin/soft tissue infections via 5
Visual rash/lesion
Culture and sensitivity (exudate/blood)
PCR lesion exudate
Medical imaging
Serological testing
difference between culture/sensitivity and PCR lesion exudate
phenotype vs genotype of infectious agents are identified
what is the cause of inflammation symptoms
increased local blood flow
production of vasoactive mediators
symptomatic management includes
The discomfort associated with skin, soft tissue, and bone infections can be relieved by cold compresses, elevation/offloading, analgesia or non-steroidal anti-inflammatory medication.
drainage does what
removes growth medium for infectious agent
irrigation does what
removes debris and microbial toxins
visuals of wound bed
wound hydration
debridement does what
removal of necrotic tissue
removal of endogenous toxins
dressing does what
sterilisation
why is penicillin a common first line drug
-targets gram-positive cocci which is common
-they are bactericidal which can progress rapidly
what is the most common human infection
skin and soft tissue infections
what % is caused by community acquired MRSA
60
Bacterial infections can be caused by what kind of microbiota for skin infections
endogenous or exogenous
how do viral infections cause skin infections? 2
the virus replicates in the epithelial cells and remain localised or
systemic that result in skin signs of infection and a systemic host inflammatory response (chickenpox)
what is impetigo
a bacterial epidermal infection thats caused by disruption to skin integrity by insect bites or eczema.
it can be
bullous- caused by staph auerus
non bullous- staph and Group A strep
folliculitis is what
a bacterial/viral or fungi infection caused by hair follicle infection/inflammation, precipitted by epidermal abrasion
can be caused by shaving or exfoliation
acne infection is what
bacterial infection of the hair follicle and associated sebaceous gland. Results in lesions being formed
eryipelas is what
a dermal (upper dermis and lymphatics) bacterial infection, causing an erthematous rash with a clearly demarcated edge. Usually preceded by systemic signs and symptoms therefore considered a systemic infection
cellulitis is what
a systemic bacterial infection of deep dermis and subcutaneous tissue. a rash presents but does not have a clear demarcation zone. it is associated with comorbid conditions.
what type of virus is herpes simplex
latent
tinea is also called ? and what is it?
ringworm.
fungal skin infection caused by dermatophytes that infect keratinised layers of skin (use keratin as nutrient source)
tinea verscolor is what
a superficial yeast skin infection
pigment production is disrupted during infection leading to reversal of the usual skin tone
candidiasis is what
opportunisitic yeast skin infection
occurs in areas that are warm, moist and macerated
all wounds are considered what ?
contaminated because there is an opening to environment
