wk 9 - RA

Question 1

ankylosing spondylitis

Answer 1

A systemic, progressive disease of inflammatory of the spine, leading to
fusion

Question 2

AS clinical features

Answer 2

• nocturnal back pain/ stiffness with or without systemic symptoms
• achillies/patellar tendonitis

Question 3

AS management

Answer 3

1. exercise - reduce stifness/loss of function
2. NSAIDs
3. bDMARDs , CS dont work
   -increased risk of low level infections
4. surgery

Question 4

complication of AS

Answer 4

enethesitis in foot

Question 5

psoriatic arthritis

Answer 5

chronic inflammatory arthritis that occurs in people with psoriasis of the skin or nails
(may precede or follow skin involvement)

Question 6

PsA clinical features

Answer 6

• sausage toes
  -have psoriasis first usually
• nail changes
• arthritis mutilans

Question 7

how long after does PsA develop

Answer 7

10 years after psoriasis

Question 8

what is arthritis mutilans

Answer 8

Resorption of bone (osteolysis) small joints of digits

Question 9

PsA management

Answer 9

1. NSAIDS
2. corticosteroids
3. csDMARDs- not hydrocycholorquine makes psoriasis worse
4. bDMARDS

Question 10

reactive arthritis

Answer 10

caused by infection

Question 11

clinical features of reactive arthritis

Answer 11

1. conjunctivitis
2. urethritis
3. arthritis
4. mucocutaneous symptoms

Question 12

Reactive arthritis management

Answer 12

1. NSAIDS
2. corticosteroids
3. antibiotics
4. csDMARDs/ bDMARDs

Question 13

spondyloarthropathies have what?

Answer 13

absence of rhematoid factor in serum

genetic association with HLA B27

present with enthesitis, dactylitis, tendonitis

Question 14

scleroderma

Answer 14

rare chronic disorder with diffuse fibrosis of the skin and internal organs

Question 15

triggers to sclerderma

Answer 15

1. injury
2. drugs
3. chemicals

Question 16

clinical features of scleroderma

Answer 16

joint/muscle pain and stiffness
increased sensitvity to cold
digestive problems
skin changes- hard tight skin

Question 17

raynauds phenomonon

Answer 17

hyperactivation of the sympathetic nervous system causing extreme
vasoconstriction of the peripheral blood vessels, leading to tissue hypoxia

Question 18

complications of sclerderma

Answer 18

• raynauds
• increased collagen causing hard tight skin
• puffy hands and feet
• ulceration
• lesser toe deformities/ decreased rom
  -tightening and thickening of tendons
  -calcinosis

Question 19

systemic lupus erythamatous

Answer 19

autoimmune inflammatory connective tissue disorder predominantly effecting
young females of non white descent

Question 20

SLE clinicalfeatures

Answer 20

• redness hands/face
  -butterfly rash
  -alopecia
  -photosensitive
  -swelling around nail bed

Question 21

complications of SLE

Answer 21

-DVT risk factor

Question 22

what type of joint hypermobility is considered a disordr

Answer 22

disrupts normal function
causing pain

Question 23

how to diagnose hypermobility

Answer 23

beighton scoring sytem
1. thumb
2. wrist
3. elbow
4. knee
5. hips

Question 24

marfan syndrome

Answer 24

gene mutation of the proteins that make healthy connective tissue

Question 25

marfan syndrome clinical features

Answer 25

tall thin, armspan that exceeds ehight

Question 26

osteogenesis imperfecta

Answer 26

brittle bone disease (genetic)

Question 27

diagnosising hypermobility

Answer 27

beighton scale
2 main criteria

-4 or more beighton score
-joint stiffness longer than 3 months in 4 or more joints