wk 9- high risk foot intro Flashcards
what makes up a high risk foot
where neuropathy, ischemia, and infection lead to ulceration of the foot
this occurs when two or more risk factors are present
what medical conditions/pathologies are most common for high risk foot
- diabetes makes up 75% of foot complications
- then RA/ other systemic pathologies (15%) then
- PAD without DM (10%)
what are 3 predisposing factors for diabetics making them high risk
- peripheral neuropathy
2.peripheral vascular disease - abnormal cellular / inflammatory pathways
IWGDF high risk foot status
0- no lops or pad : examine annually, very low risk
1- lops or pad : examine 6-12months, low risk
2- lops and pad, lops and deformity, pad and deformity : examine every 3-6 months, mod risk
3-lops or pad and one of following
-history of ulcer
-amputation
-end stage renal disease
examine 1-3months, high risk
pathway to amputation in diabetics
diabetes
neuropathy
ulceration
vascular impairment (delayed healing, immunocompromised)
infection
amputation
what location of ulcer has a high recurrence rate
plantar ulcers
almost half of diabetic foot ulcers with recur within ?
1 year
what macro and micro complications do diabetes have
macrovascular: PVD, CHD, stroke
microvascular:
retinopathy
nephropathy
neuropathy
these are caused by atherosclerosis, high blood viscosity, glycosylated haemoglobin, thickened basement membrane
types of neuropathy
loss of protective sensation
motor neuropathy : weakness of muscles, deformity
autonomic neuropathy: reduced sweating (dry skin, fissures, cracking, callus)
HBA1C target for most patients with diabetes is
7% or less
what are microvascular complications linked to
Uncontrolled glucose levels which increases risk of ulceration
each 1% increase in hba1c means what
a decrease in wound healing
stages of wound healing
- bleeding (immediate)
- inflammation (appears within week 1)
- proliferation (1st week- months)
- remodelling (begins 3 weeks- 2 years)
this is normal wound healing process
these stages overlap eachother
what affects wound healing
infection
lack of blood supply
wound tension
wound pressure
deficencies
systemic conditions
immunisuppressant conditions/medications
age
how does hypergylcaemia hinder wound healing
promotes endothelial dysfunction
vascular leakage
impiared angiogenesis
activates inflammatory response
immunosuppressant
reduces WBC function