wk 2 review

Question 1

A patient has the following thyroid profile: decreased total T4, decreased Free T4, positive thyroid peroxidase antibody, increased TSH. What is the most like scenario?

Idiopathic hyperthyroidism
Hashimotos’s thyroiditis
A normal thyroid
Grave’s disease

Answer 1

Hashimotos’s thyroiditis

Question 2

The primary serum test to screen for thyroid disease is:

TSH
FT4
Reverse T3
Total T4

Answer 2

TSH

Question 3

What is the major carrier protein of the thyroid hormones in the blood?

Albumin
Thyroxine binding pre-albumin
Thyroxine binding globulin
Thyroglobulin

Answer 3

Thyroxine binding globulin

Question 4

A pregnant patient presents to her OB/GYN in the first trimester of pregnancy with abnormal ultrasound readings, normal hCG, and AFP values of 8 MoM (normal is <2 MoM). Based on this evidence, what is most likely manifesting in the fetus?

Neural tube defects
Trisomy abnormalities like Down Syndrome
This is a normal pregnancy
None of the above

Answer 4

Neural tube defects

Question 5

Which of the following is not quantified in the triple test for Down Syndrome?

Alpha-1 fetoprotein
Unconjugated estriol
Progesterone
hCG

Answer 5

Progesterone

Question 6

A laboratory measures maternal serum AFP (MS-AFP) at 16-18 weeks gestation as a screen for fetal disorders. The 16 week MS-AFP median is 32 mg/L and a 37 year old woman has a MS-AFP level of 34 mg/L. This result is consistent with:

A normal MS-AFP level for 16 week gestation
Possible neural tube defects, including spina bifida
Possible multiple birth
Possible trisomy disorder, including Down Syndrome

Answer 6

A normal MS-AFP level for 16 week gestation