Winter Test 1 (Ch. 4, 16,11,12) Flashcards
Purines
double ring
Adenine (A)
Guanine (G)
Pyrimidines
single ring
Cytosine (C)
Thymine (T)
DNA structure breakdown
DNA –> histones –> nucleosomes –> chromatid –> chromosome
process of DNA synthesis
DNA –> mRNA –> protein
transcription
step from DNA to mRNA
occurs in the nucleus where DNA is located
translation
step from mRNA to protein
most occurs in cytoplasm
Peptide formation
1) DNA double helix
2) 7 base triplets on template strand of DNA
3) mRNA transcribed
4) Anticodons of tRNA bind to mRNA codons
5) Amino acids carried by 6 tRNA molecules
6) Amino acids linked into a peptide chain
Cell cycle
G1 phase- get materials needed to replicate DNA
S phase- DNA replication
G2 phase- synthesize enzymes for cell division and repairs DNA replication errors
M phase- mitosis
G1, S, G2 are called interphase
Cells stop dividing when
snugly contact neighboring cells
when nutrients or growth factors are withdrawn
contact inhibition – no more space
Cells divide when
they have enough cytoplasm for two daughter cells
they have replicated their DNA
adequate supply of nutrients
are stimulated by growth factors
Polygenetic inheritance
genes at two or more loci, or even different chromosomes, contribute to a single phenotypic trait (skin and eye color, alcoholism, mental illness, cancer, and heart disease)
Pleitropy
one gene produces multiple phenotypic effects
Penetrance
% of population inhibiting expected phenotype
Modality of Receptors
Thermoreceptors- heat and cold Photoreceptors- eyes/light Nociceptors- pain Chemoreceptors- chemicals: odor, fluids, tastes Mechanoreceptors- vibrations, pressure
Duration of receptors
phasic- burst of action potentials, quickly adapt and sharply reduce or stop
tonic- adapt slowly, generate nerve signals more steadily
Intensity of receptors
3 ways:
which fibers are sending signals
how many fibers are doing so
how fast these fibers are firing
Origin of stimuli of receptors
exteroceptors- external stimuli
interoceptors- internal stimuli
proprioceptors- body position
Distribution of receptors
general (somesthetic) senses- widely distributed
special senses- vision, hearing, equilibrium, taste, and smell
Uncapsulated nerve endings
lack connective tissue wrapping (free nerve endings)
Tactile (Merkel) discs- tonic receptors for light touch
Hair receptors
Encapsulated nerve endings
wrapped by glial cells or connective tissue
enhances sensitivity/selectivity of response
Project pathways of sensory neurons
3 nerve orders:
1st- afferent, body to spinal cord
2nd- spinal cord to thalamus
3rd- thalamus to cerebrum
Papillae of the tongue
filliform- no taste buds (for texture)
fungiform- tips and sides of tongue
vallate (circumvallate)- 50% of taste buds
2 mechanisms of taste
Salty (Na+) and Sour (acidic)- depolarizes and change membrane potential
Umami (amino acids), Bitter (alkaloids), Sweet- 2nd messenger system
Outer ear
auricle
auditory canal- temporal bone to tympanic membrane
external acoustic meatus