Why EBM? Flashcards

1
Q

Why is evidence based medicine important?

A
  • to treat patients
  • patient safety
  • medical knowledge
  • re validation
  • professionalism
  • practice- based learning
  • communication
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2
Q

What are some of the problems with evidence based medicine?

A
  • not relevant in clinical practice?
  • takes too much time
  • confusing for patients (statistics)
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3
Q

What things is evidence used for in clinical practice?

A
  • Clinical findings and how to attain the right info and interpret it properly
  • Aetiology identification
  • Differential diagnosis
  • Diagnostic test - picking and confirming
  • Prognosis
  • Therapy selection
  • Prevention
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4
Q

What is the order of the hierarchy of studies (lowest to highest)?

A

Animal/lab studies, case report, cross sectional study, ecological study, case control, cohort, randomised control, systematic review/meta analysis

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5
Q

What are systematic reviews/meta analyses?

A

Analysing data from other trials - pooling of results

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6
Q

What is a randomised controlled trial?

A

Used to trial, manipulation of independent variable

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7
Q

What is an advantage and a disadvantage of RCT?

A

Large size needed to get good effect, expensive, missing trials can make results bias, inappropriate controls, cause and effect established

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8
Q

What is a cohort study?

A

Using a group of people before they get an illness and look retrospectively at the exposure/risk factors. Follow through to see how develops condition.

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9
Q

What is an advantage and a disadvantage of cohort studies?

A

Less prone to bias, good for common conditions, very time consuming

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10
Q

What is a case control study?

A

Those with a condition and those without are compared to look for risk factors etc. ALWAYS RETROSPECTIVE

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11
Q

State an advantage and disadvantage of case control studies

A

cheap, quick, good for rarer conditions, but retrospective so reliable?

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12
Q

What is an ecological study?

A

It is a descriptive study. Uses correlations between populations using exposures

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13
Q

What is a cross sectional/descriptive study and what is a disadvantage of it?

A

Surveys or analysis

Cannot establish cause and effect

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14
Q

What is a case report?

A

Describing one case - not used in EBM alone

- can be useful in rarer conditions

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15
Q

What is homeopathy?

A

uses principle - like causes like
diluted medicines etc.
NHS spends $4 million a year

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16
Q

How many times is the MMR vaccine given and at which ages?

A

2
Ages 12-15 months
Ages 3-5 years

17
Q

When was the MMR vaccine introduced?

A

1988

18
Q

What does the MMR vaccine do?

A

Protects against measles, mumps (highest cause of viral meningitis in kids) and rubella

19
Q

Why was the MMR vaccine discontinued and the brought back?

A

people thought they caused autism, GI problems and behavioral problems

Number of cases increased and there was no causal relationship