White Blood Cells (WBCs)

Question 1

Another name for WBCs?

Answer 1

leukocytes

Question 2

WBCs are begin formation in the _____?

Answer 2

bone marrow

Question 3

Normal WBC count?

Answer 3

5,000 - 10,000

Question 4

WBCs circulate throughout the ______ tissues.

Answer 4

lymphoid

Question 5

WBCs are responsible for the ______ & _____ response.

Answer 5

immune & inflammatory

Question 6

WBC are classified into what two groups?

Answer 6

granulocytes & agranulocytes

Question 7

All granulocytes are ______, and have the ability to engulf microbes and other substances.

Answer 7

phagocytes

Question 8

The granules within the granulocytes cytoplasm contain ______ & ________ that break down engulfed microbes.

Answer 8

chemicals & enzymes

Question 9

granulocytes are divided into which three types?

Answer 9

neutrophils, basophils, eosinophils

Question 10

Neutrophils defend against ______ & _______?

Answer 10

bacteria & fungi

Question 11

Neutrophils are ___% - ____% of WBC count?

Answer 11

55% - 70%

Question 12

Immature neutrophils are called _____?

Answer 12

bands

Question 13

A “shift to the left” means there is an ____________.

Answer 13

increase in the number of bands (immature neutrophils)

Question 14

Eosinophils are mostly found in ______ rather than circulation. Commonly the _____ & _____ tracts.

Answer 14

tissues.

GI & respiratory tracts

Question 15

Eosinophils make up ___% - ____% of WBC count.

Answer 15

1% - 4%

Question 16

Eosinophils increase to defend against ____ & ____.

Answer 16

parasites & allergies

Question 17

Basophils make up ___% - ____% of WBC count.

Answer 17

0.5 - 1

Question 18

What do Basophil granules contain?

Answer 18

heparin, & histamine

Question 19

Basophils are involved in _____ & ______ reactions.

Answer 19

allergic & hypersensitivity reactions

Question 20

Basophils release _______ .

Answer 20

histamine

Question 21

Monocytes mature into ________.

Answer 21

macrophages

Question 22

Monocytes make up ___% - ____% of WBC count.

Answer 22

2 - 8%

Question 23

Neutropenia is neutrophil < _____.

Answer 23

<1500 cells

Question 24

Agranulocytosis is neutrophil count < ______.

Answer 24

<200 cells

Question 25

Causes of Neutropenia?

Answer 25

Autoimmune disease
Bone marrow depression
Chemotherapy
Congenital
Radiation
Meds
Severe infection
Viral infections
Hematologic malignancies

Question 26

Mononucleosis “kissing disease” is caused by the _____________ virus.

Answer 26

Epstein-Barr

Question 27

Mononucleosis is transmitted via _____.

Answer 27

oral secretions

Question 28

Manifestations of mononucleosis are?

Answer 28

enlarged lymph nodes (lymphadenopathy)
sore throat (pharyngitis)
increased wbc

may be asymptomatic for 4-8 wks

Question 29

__________ cell is present in Hodgkin’s Lymphoma.

Answer 29

Reed-Stenberg cell

Question 30

Manifestations of Hodgkin’s Lymphoma:

Answer 30

enlarged, painless lymph nodes
weight loss
night sweats
associated with Epstein-Barr virus (EBV)

Question 31

Malignant cells in lymphoid tissue that do not have Reed-Stenberg cells are called _______.

Answer 31

Non-Hodgkin’s Lymphoma

Question 32

Risk factor for leukemia in children is _____.

Answer 32

down syndrome

Question 33

Leukemia is classified by _____ & ______.

Answer 33

cell type and duration

Question 34

Symptoms for active myeloma:

Answer 34

CRAB

C= calcium; high
R= renal problems
A= anemia
B= bone problems

Question 35

_______ proteins are excreted in the kidneys due to their low molecular weight. (in myeloma)

Answer 35

Bence-Jones