Anemia Flashcards

1
Q

Anemia is defined as abnormally _______.

A

low red blood cells and or hemoglobin

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2
Q

Causes of anemia?

A

1 - excessive loss of RBCs from bleeding
2 - destruction of RBCs (hemolysis)
3 - defective RBC production
4 - inadequate RBC production d/t bone marrow failure

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3
Q

Anemia is not a disease, but an indication of ______.

A

an alteration in body function or disease process

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4
Q

Anemia causes tissue _____.

A

hypoxia

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5
Q

Signs/symptoms of anemia?

A
chest pain (d/t lack of O2 to heart)
dizziness (d/t lack of O2 to brain)
headache (d/t brain cells dying; hypoxia)
increased HR
fatigue
SOB
palpitations
pallor
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6
Q

Blood Loss Anemia is caused by _____.

A
GI bleed
clotting problems
heavy menstrual period
hemorrhage
any injury or circumstance that causes excessive blood loss
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7
Q

What can happen during Hemolytic Anemia ?

A

excessive breakdown of RBC in the blood stream causes build up of unconjugated bilirubin; therefore causing jaundice.

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8
Q

How is Sickle Cell disease an example of Hemolytic Anemia?

A

In Sickle Cell disease the RBC sickles r/t low oxygen (hypoxia) due to a genetic disorder (intrinsic factor)

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9
Q

Extrinsic (outside the body) factors that may cause Hemolytic Anemia?

A
drugs/toxins
physical trauma
malaria
venoms
burns
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10
Q

Iron Deficiency Anemia is caused by

A

not enough iron

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11
Q

What can cause low iron in the body?

A

Inadequate dietary intake
Excessive iron loss through bleeding
Increased iron demands

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12
Q

Iron is a component of _____.

A

Heme

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13
Q

A deficiency of heme leads to decreased hemoglobin synthesis, that leads to an impairment of _______.

A

oxygen delivery

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14
Q

Chronic blood loss can lead to ____ deficiency.

A

Iron

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15
Q

Example of chronic blood loss condition?

A

GI bleed

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16
Q

Manifestations of iron deficiency?

A

Brittle hair & nails
Deformed spoon shaped nails
Pica
Smooth tongue

17
Q

The ______ test is used to diagnose B12 Anemia.

A

Schilling

18
Q

Pernicious anemia is caused by failure to produce _____.

A

intrinsic factor

19
Q

B12 can not be absorbed when there is a lack of ______.

A

intrinsic factor

20
Q

Failure to produce intrinsic factor is caused by ________.

A

autoimmune, atrophic gastritis, gastrectomy

21
Q

People with B12 anemia will need ______ for life.

A

B12 replacement

22
Q

A reduction in all types of blood cells is called ______ anemia.

A

Aplastic

“Pancytopenia”

23
Q

Treatment for aplastic anemia?

A

Bone marrow transplant

24
Q

Aplastic Anemia may be caused by:

A
viral illnesses (AIDs)
Hepatitis
radiation
neutropenia
thrombocytopenia
25
Q

Mean Corpuscular Volume (MCV) is _____

A

the size of a cell.

26
Q

Normocytic is

A

normal cell volume

27
Q

Microcytic is

A

low volume

28
Q

Macrocytic

A

high volume

29
Q

Hypoxia causes kidney to sense decreased O2 and produce more ________.

A

erythropoietin