Red Blood Cells (RBCs) Flashcards

1
Q

Another name for RBC?

A

erythrocyte

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2
Q

What is the main function of RBC?

A

carry oxygen to tissues

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3
Q

RBC is made of a protein called?

A

hemoglobin

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4
Q

RBC life span?

A

120 days

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5
Q

Blood is made of?

A

RBCs, WBCs, platelets. Suspended in plasma

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6
Q

Normal RBC count for women?

A

4.2 - 5.4 /ul

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7
Q

Normal RBC count for men

A

4.7 - 6.1 /ul

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8
Q

Hemoglobin can carry ______ molecules of oxygen.

A

4

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9
Q

RBC production begins in the _________.

A

bone marrow

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10
Q

Peritubular cells in the kidney sense decreased oxygen (hypoxia), then produce a hormone called ______.

A

erythropoietin

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11
Q

The release of erythropoietin by the kidneys stimulates the bone marrow to _____.

A

produce more RBCs

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12
Q

The destruction of RBCs is facilitated by phagocytic cells found in the _______.

A

liver, spleen, bone marrow, and lymph nodes

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13
Q

Heme from destroyed RBC is converted into ____?

A

bilirubin

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14
Q

Bilirubin is removed from the blood by the _____ and conjugated to make it water soluble.

A

liver

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15
Q

The plasma-insoluble form of bilirubin is referred to as ________ bilirubin.

A

unconjugated

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16
Q

The water-soluble form of bilirubin is referred to as ________ bilirubin.

A

conjugated

17
Q

What condition happens when RBC destruction takes place in the blood, causing excessive build up of bilirubin, and yellowing of the skin?

A

jaundice

18
Q

How tightly hemoglobin is bound to oxygen is referred to as _____?

A

affinity

19
Q

Oxygen binds with hemoglobin to form?

A

oxyhemoglobin

20
Q

Increased affinity =

A

↑pH, ↓CO2, ↓temp

21
Q

Decreased affinity =

A

↓pH, ↑CO2, ↑temp

22
Q

A condition where there are abnormally high (too many) RBCs with increased Hgb & Hct is called _______

A

polycythemia

23
Q

A rare neurologic syndrome caused by excessive unconjugated bilirubin in infants.

A

Kernicterus

24
Q

Increased bilirubin is treated with ______.

A

phototherapy

skin needs to absorb light to convert bilirubin making it soluble