What Is The Fucntion Of Connective Tissue Flashcards
What forms the ECM of ordinary connective tissue and cartilage?
Fibroblasts and chondroblasts
ECM = fibres + ground substance
What is the structure of the extracellular matrix?
Ground substance Reticular fibres Collagen fibre Elastic fibre Adipocytes Mast cells Fibroblasts WBCs BVs
What does the ECM consist of?
Fibres (fibrous proteins) + ground substances (gel)
What are reticular fibres and their function?
Made of collagen and glycoproteins
Provide support in blood vessel walls and form branching networks
What are collagen fibres and their function?
Strong, flexible bundles of protein collagen (most abundant protein in your body)
What is the ground substance and its function?
Material between cells and fibres
Made of water and organic molecules (hyaluronic acid, chondriotin sulphate and glucosamine)
Supports cells and fibres
Provides a medium for exchanges substances
What are elastic fibres and their function?
Stretchable but strong fibres, made of proteins, elastin and fibrillin
What are fibrocytes?
Long and thin cells and produce the majority of the ECM
What are the constituents of the ECM?
Collagen fibres
GAGs
What are some examples and function of ordinary connective tissue?
Areolar: skin
Supports epithelial lining of the GI, resp and urinary tracts
Loose packing between cells of other organs
Adipose: fats
Brown adipose (thermoreg)
Reticular: lymph nodes
Reticulin protein
What are some examples of dense connective tissues?
Irregular: skin
Collagen positively charged attracting acid stains
Regular: skeletal muscle
Elastic: aorta
What are some examples of liquid connective tissue?
Blood and lymph
Cells: blood cells
ECM: plasma or lymph
What is the function of the basement membrane?
For cell adhesion, diffusion barrier and reg of cell growth
Describe cell adhesion of the basement membrane?
Fibrils link cell with ECM
What are examples of specialised connective tissue?
Hyaline: cartilage (chondrocytes, chondroblasts immature cells which secrete matrix, lie on cartilage surface called perichondrium)
Fibrocartilage (tendon)
Elastic (ear)