What is AIDS?

Question 1

What does AIDS stand for?

Answer 1

Acquired ImmunoDeficiency Syndrome

Question 2

When was AIDS first discovered?

Answer 2

1980s

Question 3

When is the earliest known evidence of AIDS existence? How was it discovered?

Answer 3

1950’s. HIV found in blood sample of African patients.

Question 4

What was the origin animal of HIV-1 ?

Answer 4

Chimpanzee

Question 5

What was the origin animal of HIV-2?

Answer 5

Sooty Mangabey

Question 6

Why does HIV not cause disease in chimps?

Answer 6

HIV uses CD4 cellular receptors which cannot bind with chimps.

Question 7

What are the clinical features of AIDS?

Answer 7

Huge reduction in circulating CD4+ T cells. Severe recurrent infections. High incidence of aggressive cancer. B-cell lymphoma.

Question 8

Give examples for infections that signified the presence of AIDS?

Answer 8

Pneumocystis carinii (pneumonia). Kaposi sarcoma (cancer).

Question 9

Examples of bacterial infections of HIV?

Answer 9

T.b, Salmonella species, Mycobacterium avium intracellulare.

Question 10

Examples of HIV Fungi?

Answer 10

Candida species, Histoplasma capsulatum, Pneumocystis jirovecii.

Question 11

Examples of immunodeficient viruses in HIV patients?

Answer 11

Herpes simplex, Varicella-zoster, Cytomeglovirus.

Question 12

Examples of immunodeficient parasites in HIV patients?

Answer 12

Toxoplasma species, Leishmania species,

Question 13

Examples of malignancies in HIV patients?

Answer 13

Kaposis sarcoma, Non-Hodgkins lymphoma, Burkitts lymphoma, Primary lymphoma of the brain