Treatment for HIV

Question 1

How do anti-retroviral drugs work?

Answer 1

Rapidly clear virus from the blood and amount of CD4 T cells increase.

Question 2

Why must HIV continue to infect new CD4 cells?

Answer 2

Cells live for only a few days once infected.

Question 3

What actions does an anti-retroviral drug carry out?

Answer 3

Neutralizes antibody, complement and phagocytes.

Question 4

What are some issues HIV treatments face?

Answer 4

Drug resistance. Long-term toxicity of anti-retroviral agents.

Question 5

List some needs for prolonged survival of a HIV positive individual?

Answer 5

. Anti-retroviral agents
.Immunization
.Chemoprophylaxis
.Aggressive treatment of infections and malignancies
.Triple therapy-HAART in symptomatic patients. CD4 is below 500mm/cm^3 OR viral load is less than 50,000 copies/ml.

Question 6

What are the issues with AIDS vaccines?

Answer 6

They must have NO risk of causing disease.

Question 7

What is an issue with HIV-1 vaccines?

Answer 7

Production of memory cytotoxic T-Cells requires an infection of antigen presenting cells.

Question 8

What is preventing a HIV-1 vaccine from being produced?

Answer 8

Memory killer T-cells are required to be produced and this NEEDS antigen presenting cells to be infected.