Week Three - Blood Supply, Stroke And Development Flashcards

1
Q

What are the four initial suppliers of blood to the brain?

A

Left vertebral Artery
Right vertebral artery
Left carotid artery
Right carotid Artery

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2
Q

The common carotid artery will branch into…

A
  • The internal carotid artery
  • will supply blood to the brain
  • The external carotid artery
  • supplies blood to the facial muscles and forehead
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3
Q

After the internal carotid artery joins the circle of Willis, it divides to form…

A
  • The anterior cerebral artery (ACA)

- The middle cerebral artery (MCA)

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4
Q

Where do the vertebral arteries arise from?

A

The subclavian arteries

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5
Q

The two vertebral arteries converge to form the…

A

Basilar artery

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6
Q

What is the largest contributor of blood to the brain?

A

The middle carotid artery - supplies 80% of the blood to the brain

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7
Q

Where does the middle cerebral artery emerge and what does it supply blood to?

A
  • The lateral sulcus
  • Supplies the lateral surface of the frontal, parietal and temporal lobes
  • Supplies blood for major areas of:
  • speech
  • motor and sensory functions
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8
Q

Where does the anterior cerebral artery emerge and what does it supply?

A
  • emerges up through the midsagital surface of the brain

- Supplies the medial surface of the frontal and parietal lobes, corpus callosum, basal ganglia

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9
Q

How is the posterior cerebral artery formed and what does it supply?

A
  • The basilar artery bifurcates
  • the lateral & inferior temporal lobes
  • the lateral & medial occipital lobes
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10
Q

What artery supplies the midbrain?

A

Posterior cerebral artery

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11
Q

What artery supplies the pons?

A

Basilar artery and anterior inferior cerebellar artery

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12
Q

What artery supplies the medulla?

A

Posterior spinal artery, anterior spinal artery and basilar artery

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13
Q

What supplies the cerebellum?

A

Superior cerebellar artery, anterior inferior cerebellar artery and the posterior inferior cerebellar artery

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14
Q

What supplies the spinal cord?

A

Posterior spinal artery and anterior spinal artery

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15
Q

What is a watershed area?

A

=vascular border zones

-where small-end branches of cerebral arteries approach each other

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16
Q

Capillaries have…

A

Slower blood flow than arteries which allows for exchange of nutritive substances between blood and brain

17
Q

What is the purpose of blood?

A
  • supplies nutrition
  • glucose
  • oxygen

-removes metabolic waste

18
Q

Strokes are responsible for ? Of deaths

A

10%

19
Q

What are the two main types of vascular disruptions?

A
  • ischemia

- haemorrhage

20
Q

What are the two types of ischemia?

A
  • Thrombosis

- Embolism

21
Q

What is a thrombosis?

A
  • narrowing of an artery
  • cause by gradual accumulation of debris
  • often occurs in areas of turbulence (bends)
  • many occur during sleep/inactivity
22
Q

What is an embolism?

A

-Caused by a fragment of material travelling through circulatory system and lodges in a different artery (e.g., blood clot, tissue from tumour, plaque)

  • sudden onset
  • often during periods of activity
23
Q

What is a haemorrhage?

A
  • rupture or leak of cerebral blood vessels
  • 10-15% of CVAs
  • deprives downstream vessel of blood
  • extravascular blood puts pressure on surrounding brain
24
Q

What are the four types of haemorrhage?

A
  • intracerebral hemorrhage
  • epidural hemorrhage
  • subdural hemorrhage
  • subarachnoid hemorrhage
25
Q

What are the developments stages in utero?

A
  • preembryonic period
  • conception - 2nd week
  • embryonic period
  • 2nd - 8th week
  • foetal period
  • 9th - 38th week (birth)
26
Q

What is the critical period for brain development?

A

3 - 6 weeks after conception

-particularly when neural tube and neural crest form