Week Six/Seven: Cellular Respiration Flashcards
Cellular Respiration
- The acquisition of chemical energy from organic fuel molecules.
- Consumes oxygen and produces CO2.
- Converts energy in organic molecules (food) to ATP.
- Change in G from complete combustion of glucose= -686kcal/mol.
- Highly exergonic; drives endergonic formation of many ATP molecules
Redox Reactions or Oxidation reduction
Electrons are passed from one molecule to another
-Oxidation is the loss of an electron
-Reduction is the gain of an electron
^Both take place at the same time
NAD = Electron Shuttle
*Nicotinamide adenine dinucleotide (NAD) can oxidize or reduce metabolites.
*NAD carries electrons between reactions during respiration.
Substrate level phosphorylation
Enzymes transfer a phosphate group from an organic substrate to ADP to create ATP. Least efficient form of ATP production.
Oxidative Phosphorylation
A type of ATP production that uses the energy harnessed from the redox reactions in an electron transport chain. Most efficient form of ATP production.
3 stages of cellular respiration
- Glycolysis
- The Citric Acid Cycle (Kreb’s Cycle)
- The Electron Transport Chain
Glycolysis
Occurs in two phases: Energy investment and energy harvest. Takes place in the cytosol. Provides pyruvate for the citric acid cycle. The glycolytic production of pyruvate reduces the cytosol by increasing the ratio of NADH to NAD+
The Citric Acid Cycle (Kreb’s Cycle)
Pyruvate molecule from glycolysis is taken into the mitochondria where it’s broken down into carbon dioxide. Generates high-energy electron carriers (NADH and FADH2) and GTP.
The Electron Transport Chain/Oxidative phosphorylation
The harvested electrons are collected into the electron “shuttle” molecules of NADH & FADH2. The movement of electrons provides energy for the movement of hydrogen ions across the membrane.
ATP Synthase produces ATP
This enzyme allows for the movement of the hydrogen ion pool back across the membrane. These hydrogen ions cause the enzyme to spin like a rotor. As the enzyme spins, ADP + P turns into ATP.
How do cells make energy when oxygen is scarce?
- Fermentation
-Fermentation Reactions Regenerate Electron Carriers
-Occurs in the cytoplasm
-Produces 2 ATP molecules
-Anaerobic (non-oxygen-requiring) pathway for breaking down glucose.
-Products: lactic acid, alcohol and very small amounts of ATP
Storing excess calories/energy
Glycogen - short-term energy storage
Triglycerides - long-term energy storage
NEAT
Daily activities, such as yard work, shopping, and walking a dog.
What is NAD+ and NADH?
NAD+ is an oxidizing agent; it accepts electrons from other molecules and becomes reduced. This reaction forms NADH, which can then be used as a reducing agent to donate electrons.
Chemical equation for cellular respiration
C 6 H 12 O 6 + 6 O 2 –> 6 CO 2 + 6 H 2 O + ATP