Week 9. Regulation Of The Heart And Blood Circulation

Question 1

1.Chronotropy
2. Dromoteopy
3. Tonotropy
4. Bathmotropy
5.inotropy
6. Lusitropy

Answer 1

1. Pacemaker frequency
2. Conduction of stimuli
3. Heart muscle tone
4. Excitability
5. Contractility (with given force)
6. Relaxation ability of the heart

Question 2

Parasympathetic effects:

Answer 2

Vagus nerve
-right vagus: SA node
- left vagus: AV node + atrial muscle
- no ventricular innervation

Transmitters: Ach, effect on muscarinergic Ach receptors( M2-> Gi-> cAMP decreased)

Antagonist: Atropine

Question 3

Parasympathetic effects: effects: negative heart effects

1.negative chronotropic effect
2. Negative dromotropic effect
3. Negative bathmotropic effect
4. Negative inotropic effect
5. Negative tonotropic effect
6.negative lusitropic effect

Answer 3

1. HR decreased
2. Conduction velocity decreased (PQ interval increased)
3. Excitability decreased
4. Contraction force decreased
5. Muscle tone decreased in atrial
6. Relaxation ability decreased

Question 4

Vagus tone

Answer 4

Normal HR is 70/min not 95/min

Question 5

Operation of examination of ion and transmitters

Answer 5

1. Heart of cat fish
2. Straub cannule is put into bulbus arteriosus
3. Ligature 1
   4 connected to transducer

Question 6

CaCl2 solution(stimulation of hyper calcaemia)

Answer 6

Result: contraction force increased, HR decreased, systolic heart arrest

Question 7

0.65% of NaCl solution

Answer 7

Result: heart is exhausted

Question 8

KCl solution stimulate hyperkalaemia

Answer 8

CF de., HR de., diastolic heart arrest

Question 9

Addition of ACh

Answer 9

CF de., HR de.

Question 10

Addition of Epi

Answer 10

CF in., HR in.,