WEEK 9 NEUROLOGICAL DISEASES CONTINUED Flashcards
What does the WHO define mental health as?
- A state of well-being in which an individual realises his or her own abilities, can cope with the normal stresses of life, can work productively and is able to make a contribution to his or her community.
On average, what proportion of men will have depression and anxiety in their lives respectfully?
- 1/8 men for depression and 1/5 men for anxiety
Which age group of Australian females report the highest % of mental illness conditions?
- 15-24 year olds
What are the 6 models of health?
- Biomedical
- Social
- Humanistic
- Existential
- Transpersonal
- Religious
What are 9 barriers to mental health services?
- Non-recognition- by patient and/or doctor
- Lack of “language” to describe symptoms
- Belief that it is not the domain of doctors
- Denial
- Stigma
- Distrust of doctors
- Poor medical advice
- Fear
- Failed first attempt at help seeking
Is there an association with mental disorders and homelessness, and also mental disorders and unemployment?
- Yes as of 484, 400 people that reported homelessness, 54% had a 12 month mental disorder
- For unemployment, there were 29% with a m12 month mental disorder
What are three main ways to manage mental illness that have been used?
- Pharmacological
- Psychological
- Electroconvulsive therapy
What are the three most common mental health issues managed by GPs and what is the form of management?
- Depression
- Anxiety
- Sleep
Form of management is medication (in 61.6% of cases)
What are 3 positive traits of someone with ASD?
- Attention to detail
- Honesty
- Conscientious
What are 4 negative traits of someone with ASD?
- Anxiety
- Sensitivity to light and sound
- Ned downtime
- Different “grow up” timeline
What are the unemplyoment rates of someone with autism?
- 58% of people in Aus
What are 6 things to know about someone with Autism?
- Social Anxiety
- Anxiety about unexpected changes
- Needing extra time
- Sensory sensitivities
- Stimming
- Meltdowns
Is it true that Autism affects more boys than girls?
- NO
- It is picked up in more boys than girls as it is missed in girls
What is the “medical model” of disability?
- That the problem belongs to the disabled person and we should focus on “fixing” that person’s diability
What is the “social model” of disability?
Select
Why is the brain very sensitive to oxidative damage during normal aging?
- Because of its high energy metabolism and relative low activity of anti-oxidative defense mechanisms (20% energy at rest).
What occurs with oxidative stress?
- DNA is damaged, proteins are oxidized, lipids are degraded and more are ROS produced = significant cell injury.
What are the three main sources for oxidative stress in terms of ageing?
- Endogenous sources
- Antioxidant defences
- Exogenous sources
What do endogenous sources include? (ageing context)
- Mitochondria
- Peroxisomes
- Lipoxygenases
- NADPH oxidase
- Cytochrome P450
What do exogenous sources include? (ageing context)
- UV light
- Ionising radiation
- Chemotherapeutics
- Inflammatory cytokines
- Environmental toxins
What do Antioxidant defences include? (ageing context)
- Enzymatic systems (CAT, SOD, GPx)
- Non – enzymatic systems (Glutathione, Vitamins- A C and E)
What can oxidants be good for?
- homeostasis e.g. Normal growth and metabolism
What can too much ROS lead to?
- Impaired physiological function e.g. Random cellular damage and specific signaling pathways leafing to ageing, disease and cell death**
What can not enough ROS lead to?
Impaired physiological function (just like too much ROS). This includes:
- Decreased proliferative response
- Defective host defences