week 8 part 3 gene interactions Flashcards
wild type allele
Prevalent allele in a population
o In most cases, encodes a protein that is made in their proper amount and functions normally
o Normal Allele
mutant alleles
Alleles that have been altered by mutation
o Tend to be rate in natural populations
incomplete dominance
Heterozygotes exhibited a phenotype that is distinct and intermediate between the two homozygous phenotypes
o Different phenotypes are observed with 100%, 50% and 0% protein level
o 1:2:1 ratio
· Degree to which we identify incomplete dominance may depend on how closely we examine an individual’s phenotype
o Eg. Phenylketonuria (PKU)
§ Heterozygotes appear phenotypically normally but have double the normal phenylalanine blood leve
codominance
Many genes have three or more variants in a population (= multiple alleles)
o Phenotype depends on which two alleles are inherited
single individual express both alleles in a way that leads to both traits in the phenotype
complex traits
gene interaction and epistatic gene interaction
gene interaction
occurs when a single character is controlled by the products of two or more genes
epistatic gene interaction
the alleles of one gene mask the expression of the alleles of another gene