week 7 Flashcards

1
Q

zygote

A

2 parent gametes that fertilize to form diploid cells or zygotes

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2
Q

cell cycle

A

a highly regulated series of events that lead to cell division (when cells are ready to divide they become compact)

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3
Q

cytogenetics

A

field of genetics involving microscopic examination of chromsomes

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4
Q

karyotype

A

a photographic representation of chromosomes

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5
Q

homologous chromosomes

A

in diploid species, members of a pair of chromosomes

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6
Q

eukaryotic chromosomes

A

occur in sets
on set has 23 chromosomes
22 autosomes
humans have 2 sets 46 total

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7
Q

two chromosome sets

A

diploid or 2n

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8
Q

gamete

A

sperm and eggs have only 1 set of chromosomes = haploid or n

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9
Q

interphase

A

g1
s phase
g2
m

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10
Q

G1

A

(11 hours)
first gap
accumulates molecular changes that promote progression through cell cycle

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11
Q

s phase

A

(8 hours)
chromosome replication produces 6 pairs of sister chromatids

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12
Q

G2

A

(4 hours)
nucleus breaks apart, and replicated chromosomes condense in preparation for mitosis
some growth may occur

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13
Q

M phase

A

(1hour)
sister chromatids separate during mitosis, and 2 cells are formed during cytokinesis (2 daughter cells containing 6 chromosomes each)

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14
Q

3 critical checkpoints

A

g1, g2, metaphase

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15
Q

mitotic cell division

A

cells divide to produce two new cells (daughter cells) genetically identical to the original (mother cell)

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16
Q

the spindle apparatus

A

a structure composed of microtubules, responsible for organizing and sorting the chromosomes

17
Q

mitosis

A

making 2 daughter cells from 1 original cell

18
Q

Mitosis pneumonic (stages in order)

A

PPMAT

prophase
prometaphase
metaphase
anaphase
telophase
cytokinesis

19
Q

prophase

A

chromatids condense into highly compacted structures that are readily visible by microscope
- nuclear membrane begins to dissolve into small vesicles, nucleolus no longer visible

20
Q

prometaphase

A

nuclear envelop completely fragments and spindle apparatus is fully formed
sister chromatids become attached to kinetochore microtubules from opposite poles

21
Q

metaphase

A

Characterised by pairs of sister chromatids aligned in a single row along a plane halfway between the poles called the metaphase plate

22
Q

anaphase

A

connections between sister chromatids are broken & kinetochore microtubules shorten, pulling chromosomes toward the pole to which

23
Q

telophase

A

chromosomes reach their respective poles and decondense
nuclear membranes re-form to produce two separate nuclei

24
Q

cytokinesis

A

happens quickly after mitosis
animals- cleavage furrow constricts like a drawstring to separate the cells
plants - vesicle from the Golgi apparatus from a cell plate, which forms a cell wall between the two daughter cells

25
end result of mitosis
two daughter cells with the same number of chromosomes as the mother cell barring mutations, two daughter cells are identical
26
meiosis
takes cell chromosome number and reduces it to half (diploid->haploid)
27
meiosis 1 key events
1. homologous pairs of chromosome segments form bivalent in the process of synapsis 2. crossing over results in physical exchange between chromosome segments from the bivalent
28
steps of meiosis I
prophase I pro metaphase I metaphase I anaphase I telophase I cytokinesis
29
meiosis I results in...
2 haploid cells with no pairs of homologous chromosomes
30
prophase I
replicated chromosomes condense, bivalents form, and the nuclear membrane starts to fragment
31
pro metaphase I
spindle apparatus is formed, and kinetechore microtubules attached to sister chromatids
32
metaphase I
bivalents are organized along metaphase plate as a double row
33
anaphase I
segregation of homologs occur connections between bivalents break, but sister chromatids stay connected together each joined pair of chromatids migrates to one pole, while homologous pair moves to the opposite pole
34
Telophase I
sister chromatids have reached their respective poles and decondense; nuclear membranes reform producing two separate nuclei
35
meiosis II
separates sister chromatids DNA is not replicated between meiosis I and II sorting events of MII are similar to those of mitosis but starting point is different
36
mitosis - meiosis I - meiosis II
two diploid daughter cells - 2 haploid cells - 4. haploid daughter cells