week 8 cardiac cells & acids Flashcards

1
Q

Myocardial muscle contraction depends on 3 factors:

A

(1) electrical stimulation from the conduction system
(2) adequate amounts of ATP (energy)
(3) adequate amounts of the calcium ion.

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2
Q

most spinal cord ends @

A

L2

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3
Q

Hydrocephalus:

A

when too much CSF→ drain isnt working or making too much much

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4
Q

Neuron RP:
AP:

A

= -70mV
= -55mV

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5
Q

Hemostasis:

A

blood vessels being intact → constrict when shot, platelet coagulation 3 step process & making fibrin

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6
Q

Positive feedback loop:

A

exaggerate things→ childbirth release oxytocin in excess

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7
Q

bohR effect:

A

+ CO2, -pH, +temp, +BPG 2,3 → releases oxy in body

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8
Q

haLden effect:

A

-CO2, +pH, -temp, -BPG 2,3, in Lungs, hemoglobin Loves & picks up oxy

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9
Q

Met-hemoglobin:
Met-hemoglobin anemia:
methlyblue:

A

= “jacked up” not avail/ for carrying from nitrates → eating & drinking
= OD of nitrates
=antidote for met-hemoglobin

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10
Q

3 buffer systems fastest-slowest:

A

= 1. Carbonic acid-bicarbonate buffer system (relys on lung system)
= 2. Protein buffer system→ Amino-acid chains pick CO2, thus carbaminohemoglobin Hb + CO2 bc greater affinity than oxy
=3. Phosphate buffer system= (slowest buffer) kidneys w/ nephrons
Loop-diuretics→ loosens to loose water

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11
Q

H2CO3 +, PaCO2- ,pH- (acid) breathing is:

A

bradypnea

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12
Q

H2CO3-, PaCO2+, pH+ (alk) breathing is:

A

Tachypnea

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13
Q

Lipolysis:

A

cut down lipids +CO2 thus acidosis

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14
Q

Trousseau’s sign:

A

Ca binding too much and flexing in in hands “gay hand penguin”

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15
Q

ABG’s: Arterial blood gases: 3 names

A

1 step naming: look at pH lvl: compensated or uncomp/
Middle name: look at HCO3 (exhaled) resp or metabolic
Last name: HCO2 acid or alkalosis

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16
Q

Autorhythmic cells RP
AP

A

= resting potential -60mV
= Action potential -40mV

17
Q

Contractile cells RP:
AP:
Cell gap junctions “doors” with rhythmic cells:

A

= Resting potential -90mV
= Action potential -85mV
= SA node cell gives ions (Na + Ca) to contractile cell

18
Q

Rapid influx of what ion depolarizes a cardiac autorhythmic cell?

A

Calcium

19
Q

Slow influx of what ion brings a cardiac autorhythmic cell from RP-AP:

A

Sodium

20
Q

Efflux of what ion repolarizes a cardiac autorhythmic cell?

A

Potassium

21
Q

blood travels into an area of the body where there is +CO2, +temp, -pH, hemoglobin should do what to oxy & effect name:

A

= Decrease it’s affinity to oxygen:
= Bohr

22
Q

Neuron RP:
AP:

A

= -70mV
= -55mV

23
Q

Before Angiotensin I is converted to Angiotensin II, it must mix w/ what that is found in the lungs.

A

=angiotensin Converting Enzyme

24
Q

Slow influx of what ion gets a neuron from RP (-70 mV) to AP(-55 mV)?

A

= Sodium

25
Q

Normal ratio of bicarbonate ions to carbonic acid in healthy adult PT:
Respiratory acidosis ratio:
metabolic acidosis:

A

= 20:1
= 20:4
= 15:1

26
Q

What is the main preganglionic neurotransmitter of sympathetic NS:

A

= Acetylcholine

27
Q

What is main neurotransmitter of entire parasympathetic NS, both pre & post ganglionic:

A

= Acetylcholine

28
Q

What cells in the kidneys monitor BP & will the release renin if detect poor perfusion?

A

= JG cells

29
Q

Efflux of what ion is responsible for a cardiac contractile cell to repolarize:

A

= Potassium

30
Q

Involuntary control of the body are subdivisions under which branch

A

Autonomic branch

31
Q

When neuron reaches AP, rapid influx of what ion causes depolarizing?

A

Sodium

32
Q

blood travels into where there is -CO2,-temp,& +pH, hemoglobin should what to oxy & is what effect:

A

= Increase its affinity towards oxygen
= haLdene effect

33
Q

rapid influx of what ion depolarizes a cardiac contractile cell:

A

Sodium

34
Q

main postganglionic neurotransmitter of the sympathetic nervous system & it’s exception:

A

= Sodium
= Sweat glands

35
Q

After a cardiac cell depolarizes & repolarizes, the Na/K pumps kick in to move ions back to their starting positions. When these are working, they pump how many Na out & K in the cell during each cycle?

A

= 3 Na
= 2 K

36
Q

BP formula:
CO formula:

A

= BP=(SV X HR) X SVR
= CO = SV X HR

37
Q

Chronotropy:
Dromotropy:
Inotropy:

A

= Heart rate
= Speed of impulses (heart)
= Contraction force (heart)