Week 5 basic Pharm Flashcards
Drug:
Medication:
Foreign to body
for medicinal purposes
Chemical name:
Generic name:
Official name:
Brand name:
=least common EX 7-chlor-1-3dihydro….
=directly manufactured EX Ibuprofen (captialized)
=name registered listed with USP EX Diazepam, USP
=name by company followed by trademark/propriety EX motrin advil
Medication profile components:
Names, class, Pharmacodynamics, Pharmacokinetics, contra/indications, admin/ routes, dose & how carried, adverse effects (unintended effects, untoward effects), special considerations,
Where meds come from:
plants, animals, minerals, synthetic (lab-made),
Nightshade plant
Atropine
Foxglove plant
Digoxin
Harrison narcotic act (1914)
“Hell Nah” aimed a controlling the importation, manufacture, & sale of opium & coca plant & its derivatives
FDA & cosmetic act (1938)
truth-in-labeling cause→ state whether the prep contains habit-forming drugs and its%
Durham-Humphrey amendments (1951)
“DR” Requires pharmacists to have either a prescription for certain meds
Kufauver-Harris amendment (1962)
amendment to FDA & C, → mandates pharmaceutical manufacturers to list complications
Drug abuse (1970)
classifies the drugs used in medicine into 5 different schedules
Schedule 1 med:
Schedule 2 med:
Schedule 3 med:
Schedule 4 med:
Schedule 5 med:
=never give, highest abuse potential
=high abuse may have dependence w/ med ind/s (codeine, morphine)
=less abuse potential low dependence (acetaminophen)
=low abuse potential = benzos (diazepam, lorazepam
=lowest abuse potential w/ lil bits of opioids often for cough/ diarrhea
Phase 1 med study
Phase 2 med study
Phase 3 med study
Phase 4 med study
=meds/ pharmacokinetics, toxicity, safe dose (therapeutic dose)
=tested on limited population
=refined therapeutic dose; collects data on side effects
= post-marketing analysis during conditional approval
FDA pregnancy category A:
FDA pregnancy category B:
FDA pregnancy category C:
FDA pregnancy category D:
FDA pregnancy category X:
= studied a lot and had not showed harmful effects to fetus/mom
=animals studies not showed harmful effects but not humans
=animals studies maybe problem w/ no studies on preg/ mother or no good studies on animals/pregnant
= fetal risks have been demonstrated benefits could outweigh risks
=fetal risk demonstrated risk outweighs possible benefits to mother
Pharmacokinetics:
Pharmacodynamics:
=how body works to med
=how med works to med
