Week 8-Blood Flashcards

1
Q

Do erythrocytes (RBC) have a nucleus?

A

no

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2
Q

Do platelets have a nucleus?

A

no

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3
Q

Do leukocytes (WBC) have a nucleus?

A

yes

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4
Q

What percentage of blood is plasma?

A

55%

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5
Q

What are the plasma proteins?

A
  1. Albumins- 60%
  2. Globulins
  3. Fibrogen
  4. Regulatory proteins- less than 1 %
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6
Q

Why Do erythrocytes (RBC) have no nucleus?

A

more room for heme so they can transport more Oxygen

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7
Q

what is the life span of RBC

A

120 days (recycled in spleen nd liver)

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8
Q

EPO (increases/decreses) when oxygen levels are low

A

increases

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9
Q

EPO (erythropoietin) leads to the formation of what?

A

RBC

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10
Q

What are the functions of blood?

A
  1. transport cells
  2. regulate ph/electrolytes of interstitial fluids
  3. limit blood loss (platelet)
  4. defends against pathogens
  5. distribute heat for temperature regulation
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11
Q

water makes up what percentage of plasma?

A

92%

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12
Q

What is the most abundant plasma protein?

A

albumins (60%)
globulins (35%)
Firbrogen (4%)
regulatory proteins (less than 1%)

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13
Q

What is the role of albumins

A
  • major contributor to osmotic pressure of plasma
  • transport lipids
  • steroid hormones
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14
Q

What plasma protein is -major contributor to osmotic pressure of plasma

  • transport lipids
  • steroid hormones
A

albumins

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15
Q

what is the role of globulins?

A
  1. transport ions, hormones, and lipids

2. immune functions (immunoglobulins)

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16
Q

what is the role of fibrinogen?

A
  • essential for clotting

- can be converted into insoluble fibrin

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17
Q

what are the regulatory proteins of the plasma proteins?

A

enzymes, proenzymes, hormones

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18
Q

what is Hemopoiesis

A

The cellular pathways by which the formed elements are produced.

19
Q

all formed elements come from what cells?

A

hemocytoblasts (stem cells)

20
Q

Reb blood cells Make up about __% of whole blood volume

21
Q

what cells Make up 99.9% of the formed elements

22
Q

what are the 3 components of the formed elements of blood?

A
  1. RBC (99.9%)
  2. WBC
  3. Platelets
23
Q

wha tis the most abundant of the WBC in the formed elements?

A
neutrophils (50-70%)
then lymphocytes (20-30%)
24
Q

________ makes up 95% of RBC protein

A

Hemoglobin

25
(what type of cell) recycle hemoglobin from damaged or dead RBCs
Phagocytes
26
Process for formation of red blood cells
Erythropoiesis
27
What are the 4 blood types?
A, B, AB, O | and then can add the -/+
28
what is the common name for leukocytes
white blood cells
29
lymphocytes come from what stem cell
30
where are RBCs produced?
bone marrow
31
when cells Push between cells to cross blood vessel walls and enter the tissues
diapedesis
32
what is chemotaxis
when WBC —Move toward specific chemicals released by bacteria or injured cells
33
Myeloid stem cells produce
1. Granulocytes (three types) | 2. Monocytes (future macrophages)
34
Lymphoid stem cells produce _________
lymphocytes
35
what is the production of lymphocytes called
lymphopoiesis
36
Processes that stop the loss of blood from a damaged vessel
Hemostasis
37
What are 3 3 phases of hemostasis?
1. vascular- blood vessel contracts 2. platelet- platelets form 3. coagulation- blood clot/clotting factors
38
Extrinsic pathway for clotting is triggered by _________
endothelial cells or peripheral tissues
39
Intrinsic pathway for clotting is triggered by _________
platelets
40
is there a greater percentage of formed elements or plasma in the blood?
plasma (55% of blood)
41
within the formed elements of the blood, which of the following is most abundant: red blood cells, white blood cells, platelets?
red blood cells (erythrocytes)
42
________ makes up 95% of RBC protein
Hemoglobin
43
_____ stem cells give way to the erythrocytes, monocytes, granultcites, and platelets
myeloid stem cells
44
what 2 granulocytes are phagocytic?
neutrophils and Eosinophils