Week 7: Recording AEPs Flashcards

1
Q

what are the major stimulus parameters in measurement of AEPs (7)

A
type
duration
rate of presentation
polarity
intensity
transducer
masking
*the consequences of choosing an inappropriate stimulus parameter vary greatly
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2
Q

stimulus type for AEPs

A
  • click stimulus
  • –100 microseconds of full on stimulus
  • –commonly ised for ECochG and ABR
  • –flat spectrum to an extent
  • –associated with the basal part of the cochlea
  • chirp stimulus
  • –presents frequencies in sequence from low to high and can be broad band or narrow band
  • –CE-chirp= gives greater response amplitude because all frequencies hit brainstem at the same time
  • tone burst or tone pip stimulus
  • –based on the length of rise-plateau-fall time in msec or cycles
  • –frequency specific with energy around the fundamental frequency
  • –commonly used in ABR
  • –give info on HL configuration
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3
Q

gating

A

*how the rise and fall time creating the envelope is constructed
—blackman is the best to use with tone burst
(controls most of the splatter)
—-modulating rise/fall times=gating
—triangular= linear envelope

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4
Q

stimulus intensity of AEP stimulus

A

*latency decreases and amplitude increases with greater stimulus intensity
*intensity does not affect all APs in the same way
*5 references may be used to describe intensity f stimulus:
dB SPL, dB peSPL, dB HL, dB SL, and dB nHL

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5
Q

calibration of brief stimuli

A
  • done with oscilliscope to measure voltage of the click and increase intensity level of 1000 Hz pure tone until = voltage and that is the pe SPL
  • difference between dB nHL and dB SPL= about 30 dB
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6
Q

stimulus presentation rate

A

*is a parameter that must be selected by the clinician in any AEP measurement
*fast rate to stress the aud nerve vs slow rates for more robust responses
no single correct stimulus rate is appropriate for all pts under all test circumstances

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7
Q

stimulus polarity

A
  • condensation= positive polarity
  • rarefaction= negative polarity
  • –there is some difference in latency between these two because negative is excitation and positive is inhibition
  • rarefaction= switches between condensation and rarefaction and then averaging
  • **polarity of acoustic stimulus depends on whether the diaphragm of the transducer moves outward or inward in producing the sound
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8
Q

transducers

A
  • a device for converting energy from one form to another
  • used in AEP receive an electrical signal and produce a sound that is often presented as an air-conducted stimulus
  • –some are done with bone conduction
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9
Q

insert earphones for AEP

A
  • very important to use a set of insert earphones compatible with auditory evoked system (selected by manufacturer)
  • advantage of inserts:
  • –increased intra-aural attenuation
  • –increased reduction of ambient noise
  • –prevent ear canal collapse
  • –increased pt comfort
  • –reduce chance for stimulus artifact
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10
Q

supra-aural earphones

A
  • correct placement of the earphone-cushion is important
  • –ensure that the earphone diaphragm is directly aligned with the EAC and pressed against the pinna with no air leaks
  • –instruct the pt not to move the headset
  • –higher chance for stimulus artifact
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11
Q

stimulus artifact

A
  • headphone use electromagnetic field to move diaphragm, when the headphone is near or on the electrode, it can pic that up
  • inserts on the other hand have a long tube and you can place the transducer away
  • –25 cm long tube
  • shielding= trying to reduce this more (tin foil on transducers)
  • alternating click polarity is helpful to reduce hat at times
  • control runs= of you pinch the tube and dont allow signal through to EAC and still see sine wave response, it is a stimulus artifact because ear isnt hearing it
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12
Q

bone-conduction oscillator

A
  • the ABR is commonly recorded with bone stimulation
  • ensure the bone oscillator is placed on the mastoid bone
  • artifact an maximum outputs are challenges to BC
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13
Q

acquisition factors of AEPs

A
  • electrode type
  • electrode location
  • analysis time (epoch)
  • averaging (sweeps=number of stimuli presented)
  • amplification
  • filter settings
  • —the type of AEP and it’s success is determined by these factors
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14
Q

electrodes basics

A
  • sensors that are placed on the skin or in some other location as close as clinically possible to the generator of the response
  • plug into preamplifier, and the response is compared between several electrodes
  • made up of different materials and come in different shapes and sizes (metal, disposable)
  • conventional is the disc (cup)
  • –gold, silver, or silver coated using silver chloride
  • –earclip electrodes are a variation of the disk electrodes
  • ear-canal electrodes (tiptrode or TM/tymptrode)
  • disposable single use electrodes are usually made of foam or cloth
  • –snap electrode or entire lead
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15
Q

electrode placement basics

A
based off of the international 10-20 system which is a road map allowing us to describe electrode locations
*has 4 starting points
---nasion= nose bridge
---inion= bump at back of skull
---pre-auricular point both left and right 
**c=central
**z=midline
**f=frontal
**t=temporal
**o=occipital
**a=earlobe
**m=mastoid
odd #=left; even #=right
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16
Q

non-inverting electrode

A
  • positive electrode
  • located at the cz of fz location
  • electrical activity (response) is not inverted when it enters the pre-amplifier
17
Q

inverting electrode

A
  • negative electrode
  • located by the ear
  • electrical activity (response) is inverted when it enters the pre*amplifier
18
Q

electrode impedance

A
  • the opposition of the current flow
  • flows through the easiest path
  • skin potentials=voltage between inside and outside of skin; directly affects the impedance
  • **skin preparation (alcohol prep pad and nuprep)
  • —-ten 20 conductive gel can also be used
  • low electrode impedance (less than 5 kilo-ohms) and balance inter-electrode impedance within 2 kilo-ohms)
19
Q

Epoch

A

a window that is time-locked to a stimulus, may contain a pre-stimulus period, as well as containing the time period after the presentation of each stimulus during AEPs

  • –always quite short (5-600 ms)
  • analysis time in measurement of AEPs must be long enough to encompass the response of interest under all test conditions
20
Q

A/D converter with signal averaging

A
  • amplitude resolution= the more fine the resolution, the more is seen
  • temporal resolution= again the more fine (smaller) the sampling, the more accurate to the actual response
  • – at least 2 pts/cycle=nyquist theorem
21
Q

addresses

A
  • vertical lines at fixed time placed at equal intervals throughout the window
  • analysis window (epoch) has a fixed number of addresses
  • AEP response is time locked
  • EEG activity is examined at each address in the analysis window after being converted from analog-to-dialog
22
Q

aliasing

A
  • folding back- extra frequencies causing distortion
  • not enough temporal resolution (# or addresses)
  • solution: set the low-pass end of he bandpass filter at or lower than the nyquist frequency
  • –basically, if the highest frequency which can be seen with sampling rate is frequency at which the ow pass is set, this way it can’t sample frequencies it wont ample appropriately
23
Q

differential amplification

A

identifying the AEP in the background noise is very important, yet tricky

  • differential amplification is used to identify the response and reject noise, and results from:
  • –amplification
  • –common mode rejection
  • –artifact rejection
  • –averaging
24
Q

amplification

A

an amplifier is a device that increases the strength of a signal

25
Q

common mode rejection

A
  • inverting electrode changes polarity of the response, while non-inverting keeps response polarity the same
  • noise will have a similar polarity in the scalp, therefore canceled out when the inverting electrode changes polarity
  • response becomes enhanced : early waves have different polarity
26
Q

artifact rejection

A
  • extreme values or outliers in the measurement
  • recording outside the preset levels are discarded
  • if excessive voltage is found (noise) at any address of the analysis window, this sample in the buffer will be removes
  • then signal is sent for averaging
27
Q

averaging

A
  • during a signal averaging process, a response is summed and periodically divided by the number of stimuli presented
  • the background noise will have a different voltage for each sweep-random
  • –for some stimulus presentations, voltage will be positive, and for other stimulus presentations voltage will be negative
  • –summing these random positive and negative values gradually reduces the background activity voltage toward zero
  • averaging is completed after filtering
28
Q

filtering

A
  • filter settings are chosen to eliminate unwanted non-response activity while preserving the actual response
  • filters reject electrical energy at certain frequencies and pass energy at other frequencies
  • a bandpass filter generally selected
  • –high pass filter-removes lower freqs from the recording
  • –low pass filter- removes higher frequencies from the recording
  • notch filter can used as well
29
Q

three types of noise which need to be filtered

A
  • radio-frequency (RF) noises comes from various sources:
  • –cell phones, pagers, intercoms, etc
  • –FM-systems, FM-radio
  • –wireless computer networks used in many hospitals
  • –medical equipment
  • –powerline noise (mostly 60 Hz)
  • –physiological noises
30
Q

how is an AEP acquired

A
  • amplified and common mode rejection is applied
  • artifact rejection and filtering is completed
  • output is sent to A/D convertor to be sampled and averaged
  • AEP is displayed for analysis