Week 7: Neurological Flashcards
Cranial nerve 1
olfactory; sensory, smell
Cranial nerve 2
optic; sight/vision
Cranial nerve 3
oculomotor; muscles of eye
Cranial nerve 4
trochlear; motor, oblique muscle
Cranial nerve 5
trigerminal; motor: muscle for mastication, sensory: head, neck, sinus and meninges
Cranial nerve 6
abducens; motor, lateral rectus muscle
Cranial nerve 7
facial; motor: facial expression, sensory: ear membrane
Cranial nerve 8
vestibulocochlear; sensory, hearing and balance
Cranial nerve 9
glossopharyngeal; sensory: tongue, motor: parotid gland
Cranial nerve 10
vagus; sensory & motor, pharynx, larynx, neck, thorax and abdomen
Cranial nerve 11
accessory; motor, trapezius and sternocleidomastoid
Cranial nerve 12
hypoglossal; motor, tongue muscles
Effects of intracranial pressure (ICP)
obstruct cerebral blood flow, destroy brain cells, displace brain tissue, brain ischeamia
Pathophysiology of alterations in cerebral circulation
supplied by 2 internal carotid arteries > BP v 60mmHg > blood flow compromised > 3 regulatory factors > (C02 = vasodialation, ^ H+ = vasodilation, v 02 = vasodialation)
Define a stroke
an acute focal neurological defect caused by a vascular disorder that injures brain tissue
Pathophysiology of a stoke
central core of dying cells > receive marginal blood flow > cells continue to die unless adequate circulation returns
Ischaemic stroke
caused by an interruption to blood flow in a cerebral vessel
Thrombic ischaemic stroke
atherosclerotic plaque ruptured > formation of a clot
Embolic ischaemic stroke
embolus lodges and occludes a cerebral artery
Haemorrhagic stroke
bleeding into the brain tissue
Pathophysiology of bacterial meningitis
invading organism > endotoxins released from bacteria > inflammatory mediators released > increased production of CSF > endothelial lining becomes leaky protein and fluid leaks out > raised ICP cerebral oedema
Causative agents of bacterial meningitis in adults
streptococcus pneumonia
Causative agents of bacterial meningitis in children
escherichia coli
Causative agents of bacterial meningitis virus
enterovirus, mumos, adrenovirus
Compilations of bacterial meningitis
increased ICP, residual neurological effect (eye movement, unequal pupils, sensory loses, facial paralysis), dysphasia, seizures
Define seizure
abnormal, uncontrolled electrical discharge from a group of neurons in the cerebral cortex
Partial seizure
seizure begins in a specific of focal area of one cerebral hemisphere
Simple partial seizure
consciousness not impaired
Complex partial seizure
consciousness impaired
Signs and symptoms of partial seizures
movement, tingling & crawling sensation, visual, auditory,
gustatory or olfactory phenomena, flushing, tachycardia, hypo/hypertension
Generalized seizure
begin simultaneously in both cerebral hemispheres
Generalized absence seizure
non convulsive, disturbance of consciousness
Generalized atonic seizure
sudden, split second loss of muscle tone, leading to slackening of the jaw, drooping of limbs or falling to the ground
Generalized myoclonic seizure
brief involuntary contractions, bilateral jerking of the limbs, generalized or confined to the face, truck or one or more extremities
Generalized major-motor seizure (tonic-clonic
vague warning, shark tonic contraction of muscles with extension of extremities and immediate loss of consciousness
Define status epilepticus
seizures that do not stop spontaneously or occur in succession without recovery
Stroke risk factors
age, gender, family history, heart disease, hypertension, smoking,
Management of stroke
anticoagulants, modify risk factors, serum cholesterol
Stroke investigations
CT, ultrasound doppler, MRI, lumbar puncture
Migraine causes
illness, cranial neuralgias, musculoskeletal tension
Clinical manifestations of migraine
irritability, cold, visual disturbances, drowsiness, headache, nausea, exhaustion, mood changes
Management of migraine
medication, sleep, quiet dark environment
Meningitis clinical manifestations
severe headache, photophobia, disorientation, neck stiffness
Meningitis investigations
lumbar puncture, blood culture, test meningeal irritation
Meningitis management
antibiotics (bacterial only), antieumetics, IV hydration, treat symptoms, frequent neurological assessment, airway management, 02 therapy
aetiology of stoke
cerebral hypoxia, fever, head injury, hypoglycaemia, CNS infections, drug withdrawal