Week 7 Flashcards
Factor 5 leiden mutation has what mode of inheritance?
AD
Which pathogen is the most common cause of acute cystitis?
E.coli
What is the mechanism behind henoch-shenlein vasculitis?
IgA immune complex deposition
A 50 year old man is evaluated for persistent heartburn despite PPI twice a day for six months. His BMI is 34 and the remainder of the physical exam is normal. Endoscopy reveals persistent esophagitis and a moderately large hiatal hernia. What is the next best treatment?
Nissan-fundoplication surgery
What is the preferred treatment of FAP familial adenomatous polyposis?
Prophylactic colectomy
What is the diagnosis of the CT finding? (See Gyazo)
Dissecting Aorta
What are the diagnostic cutoffs for HbA1c and fasting plasma glucose when diagnosis diabetes?
HbA1c > 6.5
Fasting plasma glucose >126
What are the four features of tetrology of felot?
DROP - vsD, Right ventricular hypertrophy, Overriding aorta, Pulmonary stenosis
If a patient has at least a 30 pack year history within the last 15 years, what is the age range of screening with low dose CT?
55-80 years old
Name two diastolic murmurs
Aortic regurg and mitral stenosis
50 pack year smoker presents with painless hematuria. What is next best step?
Bladder cancer until proven otherwise - next best test is cystoscopy
46 year old with type 1 diabetes presents with nausea and vomiting, early satiety, vague epigastric pain for the past 6 months. History of peripheral neuropathy. What is the most likely diagnosis?
Gastroparesis
Needle-shaped crystals that are negatively birefrigent under polarized light is a characteristic of what disease?
gout
What class of drug is used to treat urge incontinence?
Antimuscarinics
What changes in PT and PTT would you see in a patient with hemophilia A?
Normal PT with prolonged PTT (TENET)
What is the next best step in management of a patient who has been diagnosed with hyperthyroidism and negative antibodies?
Radioactive iodine uptake scan
A patient on an insulin sliding scale regimen consistently records fasting morning blood glucose levels 30-40 points higher than his established goal.
Increase basal insulin dose
A teenage athlete suddenly collapses in the middle of a game and is unable to be revived despite CPR. What is the most likely cause?
HOCM
Anticipation is a feature of trinucleotide repeat diseases. Define anticipation.
Increased severity or earlier onset of disease in succeeding generations
What is the first line treatment for lyme disease?
Doxycycline
What is the first line treatment for acute pericarditis?
NSAID + colchicine
What childhood brain tumor is derived from the remnants of rathke’s pouch, often contains calcifications, and causes bilateral heminopsia
craniopharyngioma
What is the treatment for trichmoniasis?
Metronidazole
Hydrops fetalis occurs in the setting of a certain thalasemia. What is the underlying mechanism leading to this event?
Excess gamma globin chains that bind titer to oxygen