Week 7 Flashcards
Formal definition of Gestational Diabetic
GCM characterized as carb intolerance that begins or is first noticied in pregnancy.
glucose metablism in pregnancy is considered a ________ _______
diabetogenic state
Does insulin cross the placenta?
no
Why is GD not usually an issue in the first half of pregnancy?
Bc estorgen and progesterone casues a decrease in maternal glucose levels
How does estorgen and progesterone decrease maternal glucose levels?
the cause hyperplasia of pancreatic beta cells which increases maternal insulin levels.
In the second half of pregnancy you have insulin _______
resistance
In the second half of pregnancy you have increased hepatic production of ____
glucagon
INsulin requirements may ____ in second half of pregnancy
triple
_______ is responsible for two insulin degrading enzymes
placenta
what is somogyi response?
hypoglycemic response at night with rebound hyperglycemia
what is dawn phenomenon?
increase in nighttime hypergycemia
when is ist appropriate to do first trimester screening for GD?
GDM in previous pregnancy, macrosomic infant in previous pregnancy, maternal obesity, hx of stillbirth
acceptable range for 1 hr GTT
<140
rule of thumb for 3 hr GTT
- in the am after an overnight fast
- no smoking before the test
- follow unrestricted diet consuming at least 150g carb/day for three days
fetal survaillence with GD at 16-20 weeks
genetic testing, amnio, level II US
fetal surveillence with GD at 20-22 weeks
level II or serial U/S
fetal surveillence with GD at 28-32 weeks
kick counts, weekly NST, serial US
fetal lung maturaty test in GD to be doe routinly at
37-40 weeks
What will the amnio show if fetal lung maturaty is established?
PG preset and LS ration 2
When should a person with GD have postpartum GTT?
6-8wks
What is the leading global cuase of maternal and infant illness and death?
preeclampsia
definition of gestational hypertension
HTn ONLY in pregnancy
definition of preeclampsia
HTN state prior to eclampsia
definition of superimposed preeclampsia
high readiness of preeclampsia on top of chronic HTN
definition of chronic HTN
HTN either before pregnancy or dx before 20 weeks gestation and presistant after 12 weeks postpartum
HTN is diagnosed by waht reading?
140/90
What is NOT criteria for hypertensive disorder?
edema
Criteria for gestational hypertension
- detected for the first time after mid pregnancy
- NO protenuria
- Bp returns to normal after 12 weeks pp
- May have other s/s such as thrombocytopenia na depigastric discomfort
Criteria for preeclampsia
- minimum BP 140/90 after 20 weeks
- proteniuria >300mg/24 hours or greater >1+ dipstick
- increased LDH
- elevated ALT and AST
- persistant epigastric pain from swollen liver
What does HELLP syndrome stand for?
Hemolysis, elevated liver enzymes, low platalets.
What are the renal effects of preeclampsia?
- decreased GFR
- decreased clearance of protein, uric acid, and sodium
If diastolic is <100 and +1 protein…what condition?
mild preeclampsia
With preeclampsia serum creatianine and uric acid are _______
elevated
vulvar mass at 5 or 7 o clock is what?
bartholins gland cyst or abscess
what is the course of action with a positive RPR?
requires confirmation with treponemal test (MHATP or FTA-ABS)
When hcg levels above threshold and no IUP seen on transvag US, most likely _____
ectopic