Week 6- Post-Polio Syndrome Flashcards
PART 1: INTRODUCTION, POLIOMYELITIS
PART 1: INTRODUCTION, POLIOMYELITIS
Polio is a viral infection which attacks the anterior horn cells of the ________ and ______ → muscular paralysis.
-brainstem and SC
Recovery from polio ranged from quick return to baseline to temporary or permanent ________, even death.
-paralysis
Poliomyelitis generally affected ______, and was primarily occurring during the _______.
- children (could affect adults as well)
- summer
About __/___ polio patents will not have any visible symptoms.
- What are the S/Sx of polio?
- How long do symptoms usually last?
- 3/4
- Flu-like symptoms including sore throat, fever, tiredness, nausea, HA, stomach pain.
- 2-5 days
A smaller proportion of people with poliovirus infection will develop other more serious symptoms that affect the brain and SC. What are these S/Sx?
- Meningitis and encephalitis
- Paralysis or weakness in arms, legs, or both (fasciculations, atrophy, decreased DTRs
- bulbar and respiratory involvement
- Was paralysis/weakness of the arms and legs symmetrical or asymmetrical?
- What system was spared?
- ASYMMETRICAL
- sensory system spared
What S/Sx typically were the cause of death with polio?
-bulbar and respiratory involvement
Post-Polio Syndrome (PPS):
- What is Post-Polio Syndrome?
- What characterizes it?
- PPS is a condition that affects survivors of polio years after recovery from an initial acute attack of the poliomyelitis virus.
- Characterized by acute onset of weakness, atrophy, myriad of other S/Sx.
- PPS is thought to be caused by ↑ ________ demand made by the body by giant motor units that were formed during the original viral infection.
- Years of high use of these recovered but overly extended motor units adds stress to the motor neurons and over time we lose the ability to maintain increased work demands.
- ↑ metabolic demands
Post-Polio Risk Factors:
- ________ poliomyelitis
- ______ age of onset
- degree of initial ________
- Greater physical activity in intervening years
- paralytic poliomyelitis
- older age of onset
- degree of initial recovery (greater recovery = more likely PPS)
What does diagnosis of PPS include?
-diagnosis of exclusion (based primarily on symptoms and exclusion of other neurological diagnosis)
What are the (4) diagnostic criteria for PPS?
- ) Prior paralytic poliomyelitis with evidence of motor neuron loss.
- ) Period of partial or complete functional recovery after acute paralytic poliomyelitis, followed by an interval of stable neuromuscular function.
- ) Slowly progressive and persistent new muscle weakness or decreased endurance, with or without generalized fatigue/atrophy/muscle and joint pain.
- ) Symptoms that persist for at least a year.
PART 2: PPS CLINICAL PRESENTATION, MANAGEMENT, PROGNOSIS
PART 2: PPS CLINICAL PRESENTATION, MANAGEMENT, PROGNOSIS
When patients who have a Hx of polio start to demonstrate new onset of weakness, the weakness we see __________ slowly.
-progresses
