week 6 lectures (basil ganglia) Flashcards
where does the basil ganglia recieve its input from?
the cortex
what is the name of the loop that goes cortex-basil ganglia- thalamus- cortex?
the re-entrant loop
what are 4 sections of the basal ganglia? visualise where they are
visualise where the internal capsule is in a horizontal view
what is the striatum composed of?
the caudate nucleus
the putamen
what is the putamen + globus pallidus called?
the lentiform nucleus
where does information from the cortex land in the basal ganglia?
the striatum
where in the basal ganglia does information go to the thalamus from
the globus pallidus
is the basal ganglia output continuous or discreet?
there is a continuos inhibitory output that can either be increased or decreased
what are the two pathways running from the striatum to the globus pallidus
the indirect and the direct pathway
INDIRECT- striatum to globus pallidus internal segment to globus pallidus external segment
DIRECT - striatum to globus pallidus external segment
do the direct and indirect pathway do the same thing?
- they work against each other
- this is called balanced opposition
- direct pathway inhibits
- indirect pathway excites
how does the direct pathway make the thalamus more responsive
- it inhibits the basal ganglia which is inhibitive
- therefore it inhibits the inhabition leading to an excitatory change overall
how does the indirect pathway make the thalamus less responsive
striatum to Gpe cells inhibit the inhibitory output of GPe
this increases the activity in GPI
this means there is greater inhibtory output from the gpi
so the thalamus is less respnoive
does increased output from the basal ganglia lead to the thalamus being more or less responsive
more responsive, as basal ganglia output is inhibitory