Week 6 Disease Flashcards

1
Q

Disease

A

Disease
Abnormality of the structure or function of a part, organ, or system
May be felt or observed by others.
May have a known or unknown cause.
Severity of effects may be variable

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2
Q

Seven Categories of Disease:

A

1-Infection: Infectious organisms play a part in at least half of all human illness.
2. Degenerative Disease: disorders that breakdown tissues in the body.
Causes include: hereditary factors, substance abuse, infection or normal “wear and tear” and idiopathic
3. Nutritional disorders: includes either a dietary lack of nutrients or an excess of any type.
4. Metabolic Disorders: include any disruption of cellular metabolism.
5. Immune Disorders: deficiencies in the immune system, caused by either infection or hereditary factors.
6. Neoplasms: refers to cancer and other types of tumors
7. Psychiatric disorders: mental disorders
Often associated with physical disorders

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3
Q

What is predisposing cause?

A

A predisposing cause is a factor known to increase the probability that an individual will become ill
• Some causes increase susceptibility to particular diseases.

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4
Q

What is Idiopathic?

A

Idiopathic: diseases of unknown origin

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5
Q

What is latrogenic?

A

latrogenic:
diseases due to adverse treatment effects

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6
Q

What is Epidemiology

A

Etiology
Epidemiology
• The study of diseases in entire populations; includes the occurrence, distribution, and transmission of diseases.
• includes the tendency to appear in specific demographics

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7
Q

What is incidence rate

A

Number of new cases within a population in a specific time frame
/ pop size

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8
Q

What is Prevalence rate

A

Number of cases within populations in a specific time frame

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9
Q

Mortality rate

A

Number of cases resulting in death in a specific time frame.

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10
Q

What is Endemic

A

• Epidemic: Many people affected at the same time in a given region. (influenza)
• Endemic: Disease found to a lesser extent but continuously. (common cold)

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11
Q

Disease Diagnosis

A

Disease Diagnosis identifying the disease
Symptoms
• Conditions of the disease, as noted by the patient
• Subjective feelings e.g. pain, fatigue
• Signs
Evidence of the disease, noted by the attendant
• Objective indicators: evident to someone other than patient; rapid pulse, wheezing
Syndrome
Group of signs & symptoms characteristic of a disorder

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12
Q

Disease classification

A

Diseases are often classified on severity/ duration.
Acute: severe/short duration
Chronic: less severe/long duration
Subacute: between both
Prognosis: prediction of probable outcome of disease

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13
Q

Latent stage

A

Latent stage:
• no clinical signs are evident
• the incubation period,
• the time between exposure to the microorganism and the onset of the signs or symptoms.

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14
Q

Prodromal Period

A

Prodromal period
• Nonspecific, early signs
• the time in the early development of a disease when one is aware of a change in the body, but the signs ar nonspecific
• Example: fatigue, loss of appetite, or headache.

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15
Q

Health promotion promotion

A

•organizations
• The WHO
• Public Health Agency Canada (PHAC)
• The CDC (Centre for Disease Control & Prevention)

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16
Q

Infection- invasion of pathogens
What are 3 types

A
  1. Local
  2. Systemic
    • Opportunistic Infection
    • An infection that occurs because the body has been weakened by disease
17
Q

Microorganism can be transmitted?

A

Modes of transmission
Microorganisms can be transmitted:
1. directly by physical contact between individuals
2. indirectly
through touched objects, dust, or vectors (disease-transmitting organisms).

Portals of Entry (exit)
1. Skin

18
Q

What is bacteria

A

Bacteria
•Single-celled organisms
•Lack a true nucleus, but do have DNA
•Found everywhere
•Capable of locomotion using flagella -

19
Q

What is Pili

A

•Pili short flagellae-like structures, assists in gliding over surfaces & anchors organism to surface as they get nutrients

20
Q

Asexual

A

•Asexual reproduction; reproduce by binary fission independently of other organisms

21
Q

Rickettsial and chlamydiae

A

•Rickettsiae and Chlamydiae can only grow and divide with living cell, ‘obligate intracellular parasites.
•Types
1.
Anaerobic
2. Aerobic
3. Facultative anaerobes

22
Q

Cocci

A
  1. Cocci: round
    • In pairs - diplococci
    Cocci
    cOCcUs
    (gonorrhea)
    • Chains = streptococci
    • Clusters - staphylococci
23
Q

Bacilli

A
  1. Bacilli: straight thin rods.
    Bacilli
    • form endospores
    coccobacillus.
    • Tetanus, tuberculosis
    diplobacilli
24
Q

Curved rods

A
  1. Curved rods
    • Vibrios (slightly curved)
    • Spirilla (corkscrew)
    • Spirochetes (spirals, but can twist around)
25
Q

Endospores

A

•Endospores
‘spore
• Become airborne easily
• Resistant to ordinary methods of disinfection-> dangerous
• Tetanus, botulism, anthrax
• Can live in adverse conditions such as dryness for a very long time

26
Q

Viruses

A

• Extremely small microorganisms
• Composed of a core of nucleic acid (RNA or DNA)
surrounded by a coat of proteins
Classified
• Grow only within living cells & 2. whethe
“obligated intracellular
stranded &
parasites”
• Do not respond to antibiotics (antibacterial agents)

27
Q

Prions

A

• Composed solely of protein
• Even smaller than viruses How Creutzfeldt-lakob disease wor
CAUSE
CONSEQUENCE
Creutzfeldt-Jakob disease is caused
Those affected lose 1
• Slow incubation & hard
by abnormal proteins called prions
and to move propert
that are not killed by standard
memory loss. It is al
methods for sterilizing surgical
usually within one y
to destroy
equipment.
illness.
• Produces spongy degeneration of brain tissue
NORMAL DISEASE.
HUMAN
CAUSING
PROTEIN
PRION
As prions build up in cells, the
• Creutzfeldt-Jakob disease
brain slowly shrinks and the tissue fills with holes until it resembles a sponge.
in humans (C]D)
• Bovine spongiform encephalopathy (BSE) or
Mad cow disease in cows & humans

28
Q

Fungi causes

A

27 146 I_
100%
• Causes Mycotic infections
• cause very few systemic diseases
• Examples include:
1. ‘Tinea’ fungal infection
• Cutaneous fungal infection
Ring shaped rash ‘ringworm’
• Tinea pedis -> ‘athletes foot’
2. Thrush
• some resulting diseases are very dangerous and difficult to
cure.
e.g. ‘Pneumonia’ (from inhaled
enAnO

29
Q

Protozoa
4 main types

A
  1. Amebas
    • irregular mass of cytoplasm that propels itself by extending part of its cell and then flowing into the extension
  2. Ciliates
    • covered with tiny hairs called cilia
  3. Flagellates
    • long whip like filaments called flagella propel these organisms. (Giardia: contaminates water supplies)
  4. Apicomplexans/Sporozoa
    • cannot propel themselves.
    • Unable to grow without a host.
30
Q

What is Helminths
2 types
This is type 1

A

A) Ascaris- small intestinal round worm
Infest lungs or intestines
Contaminated food
B) Pin worms- hard to eliminate
Large intestine
C) Hookworms- parasites that live in small intestine
Suck blood causing Anemia
Through feet
D) Filaria worm- causes filarias
Biting insects
Cause elephantitis

31
Q

Helminths
Number 2

A

Flatworms
Tape worms, Flukes,

32
Q

Aseptic methods

A

> Procedures that kill, remove, or prevent the growth of microbes
Sepsis: pathogens in blood

Asepsis: a condition in which no pathogens are present.
1. Sterilization: kills all microorganisms
2. Disinfection: kill most microorganisms

33
Q

Gram stain

A

Gram Stain:
• Apply a bluish purple dye (crystal violet), & add iodine.
Gram-positive: GM+
• The colour remains the same (after washing with a solvent)
• Appear blueish purple
Gram Negative: GM
• the colour can be removed by the solvent
• Dyed to be visible, usually red