Week 6 Depressive, Bipolar, Substance Related & Addictive Disorders Flashcards
Remember Monamines are neurotransmitters that include:
Serotonin (5HT), Norepinephrine (NE), and Dopamine (DA).
Thinking about the adrenal glands (atop of the kidneys:
Think about when these stressors remain high for long periods of time:
Bipolar depression:
Childhood 5-6 up to age 50 with a mean onset of 21-30
Disruptive Mood Disorder Dysregulation
can occur at any age, but generally is seen btwn 20-50 with a mean of 40
We can use the SIGECAPS mnemonic to help guide our questioning:
sleep, interest, guilt energy, concentration, appetite, psychomotor, suicidality
Remember Antidepressants can activate
manic episodes in people suffering from Bipolar and mania sometimes expresses itself as loss of impulse control
Antidepressants
Citalopram (Celexa)
Fluoxetine (Prozac)
Fluvoxamine (Luvox)
Escitalopram (Lexapro)
Paroxetine (Paxil):
be very careful and do not take with herbal supplements due to adverse effects:
Sertraline (Zoloft)
SNRIs:
Desvenlafaxine (Pristiq)
Duloxetine (Cymbalta)
Levomilnacipran (Fetzima)
Venlafaxine (Effexor)
MAOIs:
Isocarboxiazid (Marplan)
Phenelzine (Nardil)
Selegiline (EMSAM) transdermal patch
Tranylcypromine (Parnate)
Tricyclic Antidepressants:
Amitryptyline (Elavil) Amoxapine (Ascendin) Clomipramine (Anafranil) Desipramine (Norpramin) Doxepin (Sinequan) Imipramine (Tofranil)
Bipolar 1 and 2
Looking at Bipolar 1 (severe mood swings from mania to depression and Bipolar 2 a milder form, characterized by milder episodes of hypomania that alternate with depression:
Patient who is Bipolar has mania remember the following mnemonic DIGFAST
What should I think about to help guide my questioning? distractibility, indiscretion, grandiosity or inflated self esteem, flight of ideas or racing thoughts, activity increase, sleep deficit, talkativeness or pressured speech.
Can bipolar 1 and 2 (mania) occur in children?
Both mood disorders can occur in children and adolescents.
What meds could we give to treat Bipolar Disorder?
1st choice: Lithium: