Week 6 Depressive, Bipolar, Substance Related & Addictive Disorders Flashcards
Remember Monamines are neurotransmitters that include:
Serotonin (5HT), Norepinephrine (NE), and Dopamine (DA).
Thinking about the adrenal glands (atop of the kidneys:
Think about when these stressors remain high for long periods of time:
Bipolar depression:
Childhood 5-6 up to age 50 with a mean onset of 21-30
Disruptive Mood Disorder Dysregulation
can occur at any age, but generally is seen btwn 20-50 with a mean of 40
We can use the SIGECAPS mnemonic to help guide our questioning:
sleep, interest, guilt energy, concentration, appetite, psychomotor, suicidality
Remember Antidepressants can activate
manic episodes in people suffering from Bipolar and mania sometimes expresses itself as loss of impulse control
Antidepressants
Citalopram (Celexa)
Fluoxetine (Prozac)
Fluvoxamine (Luvox)
Escitalopram (Lexapro)
Paroxetine (Paxil):
be very careful and do not take with herbal supplements due to adverse effects:
Sertraline (Zoloft)
SNRIs:
Desvenlafaxine (Pristiq)
Duloxetine (Cymbalta)
Levomilnacipran (Fetzima)
Venlafaxine (Effexor)
MAOIs:
Isocarboxiazid (Marplan)
Phenelzine (Nardil)
Selegiline (EMSAM) transdermal patch
Tranylcypromine (Parnate)
Tricyclic Antidepressants:
Amitryptyline (Elavil) Amoxapine (Ascendin) Clomipramine (Anafranil) Desipramine (Norpramin) Doxepin (Sinequan) Imipramine (Tofranil)
Bipolar 1 and 2
Looking at Bipolar 1 (severe mood swings from mania to depression and Bipolar 2 a milder form, characterized by milder episodes of hypomania that alternate with depression:
Patient who is Bipolar has mania remember the following mnemonic DIGFAST
What should I think about to help guide my questioning? distractibility, indiscretion, grandiosity or inflated self esteem, flight of ideas or racing thoughts, activity increase, sleep deficit, talkativeness or pressured speech.
Can bipolar 1 and 2 (mania) occur in children?
Both mood disorders can occur in children and adolescents.
What meds could we give to treat Bipolar Disorder?
1st choice: Lithium:
NOW if my client doesn’t respond to lithium:
the next choice is anticonvulsants which are incorrectly called mood stabilizers but are not
Anticonvulsants include:
Valproic acid (Depakene) and Divalproex (Depakote):
Carbamazepine (Tegretol
Lamotrigine (Lamictal):
Oxcarbazepine (Trileptal):
Alcohol withdrawal description S/S
S/S develop within few hours after cessation of alcohol intake
These S/S peak after 24 hours and then rapidly disappear UNLESS WD
DTS
6-12 hrs after the last drink the relatively mild symptoms of early withdrawal may begin to be felt, including
DTS (Delerium Tremens)
6-12 hrs after the last drink the relatively mild symptoms of early withdrawal may begin to be felt, including
Interventions for alcohol withdrawal
monitor serum electrolytes, including glucose and magnesium
orient frequently
monitor I&O
Administer vitamins (MVI, vitamin B, folic acid, thiamine, and Vit c)
Medication therapy for alcohol misuse and alcohol dependence
Meds only prescribed for clients who STOPPED drinking
Naltrexone
Acamprosate (Campral)
Disulfiram (Antabuse): Important med!!
Disulfiram adverse effects
fatigue, facial flushing, sweating, throbbing headache, neck pain, N/V, hypotension , tachycardia, Resp distress
Managing the client who misuses alcohol & managing the client who has substance misused disorder
Set limits on manipulative behavior and verbal and physical abuse
Hold the client accountable for all behaviors
Managing the client who has substance misused disorder
Behavior therapy including CBT
Drug dependency CNS depressants
include alcohol, benzodiazepines, and barbiturates and act as a depressant, hypnotic or sedative.
What are the S/S of cocaine use?
dilated pupils
Opiods intoxication
include opium, heroin, meperidine, morphine, codeine sulfate, methadone, hydromorphone
What are S/S of withdrawal?
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There are 4 formulations of buprenorphine
Suboxone sublingual film- like methadone
Subutex
Naltrexone
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Naloxone
reverse opiod overdose
Methamphetamine: highly addictive stimulant
meth molecule is structurally similar to amphetamine
Intoxication Hallucinogens
h
Inhalants
h
Marijuana
h
Other recreational and club drugs
h
Interventions: Withdrawal
Initiate seizure precautions
hydrate the client
Monitor v/s every hour, include cardiac monitoring and diagnostic tests such as ECG and cardiac markers.