WEEK 6 Flashcards

1
Q

What are the 4 types of bases used in ointments?

A

Hydrocarbon bases
Absorption bases
Water-miscible bases
Water-soluble bases

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2
Q

T or F
Ointments with hydrocarbon bases are not absorbed by the skin

A

T

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3
Q

T or F
Hydrocarbon bases are easier to apply/spread than absorption bases.

A

F

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4
Q

Name the 2 types of absorption bases

A

Non-emulsified and emulsified

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5
Q

What ingredient distinguishes non-emulsified ointments to emulsified ointments?

A

Emulsified ointments have water in them, whereas non-emulsified ointments do not.

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6
Q

T or F
Water-miscible bases are classified into five categories based on the surfactant they contain

A

F
three categories

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7
Q

Why are water-miscible ointments easier to wash off than absorption bases?

A

Whilst water-miscible ointments don’t contain any water, their emulsifying nature enables them to mix readily with aqueous secretions of the skin and be easier to wash off.

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8
Q

Name the 3 types of water-miscible base ointments

A

Anionic, cationic and non-ionic surfactants

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9
Q

Which type of water-miscible base ointment is compatible with most medications?

A

non-ionic surfactants

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10
Q

T or F
Creams are more emollient and less occlusive than ointments.

A

T

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11
Q

T or F
The main difference between creams and ointments is the amount of water.

A

T

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12
Q

What are the 2 main types of creams?

A

Oil-in-water (O/W) emulsions (aqueous creams) and water-in-oil (W/O) emulsions (oily creams)

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13
Q

Which type of cream is preferred for oral liquid emulsions?

A

Oil-in-water because the water phase is much more pleasant to taste than the oil phase

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14
Q

T or F
(regarding creams)
The ratio of the two phases (oil and water) indicates the type of emulsion.

A

F
the oil phase can be a higher percentage than the water phase in both O/W and W/O creams.

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15
Q

T or F
The emulsifying agent in oily creams are oil soluble

A

T

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16
Q

What does “thixotropic” mean?

A

Something that displays the properties of solids when left alone but displays the properties of liquids on agitation (e.g. gels)

17
Q

What are the two types of gels?

A

Hydrogels and organogels

18
Q

T or F
Pharmaceutical pastes are usually an ointment base with a small proportion of solids

A

F
large proportion of solids (50%+)

19
Q

T or F
Pastes are not suitable in moist environments

A

F
They stay in place even in moist environments

20
Q

What is the main difference between ointments and pastes?

A

a large proportion of solid material

21
Q

What is viscosity?

A

A measure of a fluids resistance to flow

22
Q

What is the official unit for force per unit area according to the international system of units (SI)?

A

the pascal (Pa)

23
Q

What type of viscosity are people referring to when they mention the viscosity of a fluid?

A

Dynamic viscosity

24
Q
A