Week 5 - Cells and Tissues Flashcards
Define Tissue
an organised aggregation of cells (and their products) that function collectively
What are the four tissue types?
Epithelial, Connective, Muscular and Nervous
Define epithelial tissue.
Sheets of cells that cover the exterior surfaces of the body, line internal cavities and passageways and form certain glands.
Define connective tissue.
Bonds cells and organs of body together and functions in protection, support and integration of all parts of body.
Define muscular tissue.
Is excitable, responds to stimuli and contracts to provide movement, has three major types (smooth, skeletal and cardiac).
Define nervous tissue
Excitable, allows propagation of nerve impulses to allow communication between different regions of the body.
What is a tissue membrane?
A thin layer of cells that cover the outside of the body, the organs, internal passageways that lead to exterior of body, and lining of moveable joint cavities.
What are the two types of tissue membranes
Epithelial membranes and connective tissue membranes
What is a serous membrane?
A type of epithelial membrane which is composed of mesothelioma (mesodermally derived epithelial tissue) supported by a layer of connective tissue.
What is the cutaneous membrane?
The cutaneous membrane is the membrane which comprises the skin
What is the structure and function of epithelial membranes?
Comprised of epithelium attached to a layer of connective tissue, the layer of the epithelial tissue line body cavities and hollow passageways that open into external environments. Covered by mucous secreted by epithelial exocrine glands.
What are the six types of cell to cell junctions?
Gap, tight, hemidesmosomes, desmosomes, adherens, anchoring
Describe tight junctions.
Interlocking membrane proteins fuse adjacent cells together, prevents the passage of water and solutes between cells
Eg/ epithelium lining intestinal tract
Describe anchoring junctions
Contains plaque (layer of protein connecting membrane proteins to microfilaments of cytoskeleton), provide strong and flexible connections, resist separation during contractile activities, three types: desmosomes, hemidesmosomes and adherens
Describe desmosomes
Occur in patches in membranes of cells, patches are made up of structural proteins on inner surface of cell membrane, cadherin (adhesion molecule) is embedded in patches and projects through cell membrane to link with other cadherin molecules of adjacent cells eg/ cardiac muscle
Describe hemidesmosomes.
Link cells to extracellular matrix, contains adhesion protein integrins instead of cadherin, look like half a desmosome
Describe Adherins.
Use integrins or cadherins depending on what they are linking to, junction characterised by presence of contractile protein actin located on cytoplasmic surface of cell membrane, actin can connect isolated patches or form belt like structure inside cell
Describe Gap Junctions
Form intercellular passageways between membranes of adjacent cells to facilitate movement of small molecules and ions between cytoplasm of adjacent cells
What are the functions of epithelial tissue?
Provide body with line of defence, allow selective control of materials across a physical barrier, secretion, sensation
How is epithelial tissue classified?
By shape (squamous, columnar, and cuboidal), and by layers (simple, stratified and pseudostratified).
What is the function of simple squamous epithelium and where can it be found?
Allows materials to pass through by diffusion and filtration and secretes lubricating substance. Located in air sacs of lungs, lining of heart, blood vessels and lymphatic vessels.
What is the location and function of simple cuboidal epithelium?
Secretes and absorbs. Located in the ducts and secretory portion of small glands and in kidney tubules
What is the location and function of Simple Columnar Epithelium?
Absorbs and also secretes mucous and enzymes. Cililated tissues located in: uterine tubes, bronchi and uterus. Non-Ciliated located in: digestive tract and bladder
What is the location and function of pseudostratified columnar epithelium?
Secretes mucous, Ciliated tissue moves mucous. Ciliated tissue line trachea and much of upper respiratory tract.