Week 5 Flashcards
What’s the most important structure for horizontal gaze found in the tegmentum of Pons?
Abducen’s Nucleus
What 2 group of neurons does the abducens nucleus contain?
- Motor Neurons
2. Internuclear Neurons
Motor neurons of the abducens nerve do what?
send axons to innervate the ipsilateral lateral rectus
Internuclear nuerons of the abducens nerve do what?
Project to the contralateral MLF to synapse on the contralateral medial rectus
What are the 4 subpopulations of neurons in the abducens nerve?
- Twitch
- Non-twitch
- Internuclear
- Paramedian Tracts
The abducens nucleus receives input for what 3 things?
- Horizontal saccades from PPRF
- VOR, OKN, & Pursuits
- Step signals from NPH and MVN
Lesions of the left abducens nucleus cause what ? What else is effected?
Left Horizontal conjugate gaze palsy
- Impaired right VOR
What 2 things are unaffected in a horizontal conjugate gaze center?
- Vergence
2. Vertical Movements
Lesions of the MLF cause what eye disorder?
Internuclear Ophthalmoplegia (INO)
INO is named by the eye with the _____ deficit.
adduction
- right eye can’t adduct, right INO
What type of nystagmus develops from INO?
Dissociated Nystagmus
When someone has one and a half syndrome, what does this mean?
- Impaired conjugate gaze to one side
2. Impaired adduction on opposite side
What’s the only surviving horizontal conjugate movement in one and a half syndrome?
Abduction of contralateral eye
Is convergence affected in one and a half syndrome?
No. convergence is unaffected
Where are the possible lesions for one and a half syndrome?
- Combined abducens nucleus and adjacent MLF
2. Bilateral INO and unilateral abducens palsy
Lesion of MLF leads to what issue?
INO
Oculomotor and trochlear nuclei receive inputs for vertical saccades from what?
riMLF
The interstitial nucleus of cajal provides what type of signals?
Step signals
The cerebellum does what?
Ensures all eye movements and gaze holding are calibrated to provide clearest vision
The cerebellum contains what 3 things?
- Vestibulo-cerebellum
- Dorsal Vermis
- Fastigial Nucleus
The vestibulo-cerebellum consists of what 4 things?
- Flocculus
- Paraflocculus
- Nodulus
- Ventral Uvula
What 3 things is the vestibulo-cerebellum important for?
- Steady gaze holding
- Smooth pursuits
- Optimal VOR
What is the stimulus to accommodation?
Blur
What is the 2nd stimulus to accommodation?
Binocular Disparity
Binocular disparity is dependent on what ratio?
CA/C
Binocular disparity is related to what eye movements?
Vergence eye movements
What’s the 3rd stimulus to accommodation?
Perceptual factors
What are the 2 types of perceptual factors?
- Proximity or size of object
2. Perspective
What’s the 4th stimulus to accommodation?
Voluntary effort