Week 4 Content Flashcards
Assessment of High-Risk Pregnancy
What is high-risk?
⚬ A pregnancy in which the life or health of the mother or fetus is jeopardized by a disorder coincidental with or unique to __________.
■ Extends through peurperium (____ weeks after birth)
⚬ Early and regular prenatal care allows for identification of risk, mortality rates decrease and outcomes improve
⚬ A pregnancy in which the life or health of the mother or fetus is jeopardized by a disorder coincidental with or unique to pregnancy.
■ Extends through peurperium (4-6 weeks after birth)
⚬ Early and regular prenatal care allows for identification of risk, mortality rates decrease and outcomes improve
Assessment of High-Risk Pregnancy
* Categories of risk:
⚬ ____________
■ Genetic, nutritional and health (medical & obstetric)
⚬ ____________
■ Smoking, caffeine, alcohol, drugs, psychologic
⚬ ____________
■ Low income, lack of prenatal care, age, parity, marital status, social determinants of health, ethnicity
⚬ ____________
■ Workplace hazards, chemicals, anesthetic gases, radiation
⚬ Biophysical
■ Genetic, nutritional and health (medical & obstetric)
⚬ Psychosocial
■ Smoking, caffeine, alcohol, drugs, psychologic
⚬ Sociodemographic
■ Low income, lack of prenatal care, age, parity, marital status, social determinants of health, ethnicity
⚬ Environmental
■ Workplace hazards, chemicals, anesthetic gases, radiation
Danger Signs During Pregnancy
- Vaginal _________ with or without discomfort
- _________ of membranes
- _________ of fingers, puffiness of face or around eyes
- Continuous, pounding _________
- _________ distubrances (blurred vision, dimness, spots)
- Persistent or severe _________ pain
- Chills or fever
- Painful urination
- Persistent vomiting
- _________ in frequency or strength of fetal movements
- Signs of preterm labor: uterine contractions, cramps, constant or irregular low backache, pelvic pressure
- Vaginal bleeding with or without discomfort
- Rupture of membranes
- Swelling of fingers, puffiness of face or around eyes
- Continuous, pounding headache
- Visual distubrances (blurred vision, dimness, spots)
- Persistent or severe abdominal pain
- Chills or fever
- Painful urination
- Persistent vomiting
- Changes in frequency or strength of fetal movements
- Signs of preterm labor: uterine contractions, cramps, constant or irregular low backache, pelvic pressure
Assessment of High-Risk Pregnancy
* Antepartum Testing: ⚬ Two major goals
■ Identify fetuses at risk for injury due to interrupted __________ so that permanent
injury or death may be prevented
■ Identity appropriately __________ fetuses so that unnecessary intervention can be avoided.
■ Identify fetuses at risk for injury due to interrupted oxygenation so that permanent
injury or death may be prevented
■ Identity appropriately oxygenated fetuses so that unnecessary intervention can be avoided.
Biophysical Assessment
- Daily Fetal __________ Count (DFMC)
⚬ Kick counts (2 types) - non-invasive
■ Count all movements in 12-hour period until fetus has moved 10 times
■ Count movement 2 or 3 times daily until 10 movements counted
⚬ If movement decreased from prior day or unable to count 10 movements, call provider
⚬ Warning sign:
■ No fetal movement for _________ is fetal alarm signal…Call provider immediately!
- Daily Fetal Movement Count (DFMC)
⚬ Kick counts (2 types) - non-invasive
■ Count all movements in 12-hour period until fetus has moved 10 times
■ Count movement 2 or 3 times daily until 10 movements counted
⚬ If movement decreased from prior day or unable to count 10 movements, call provider
⚬ Warning sign:
■ No fetal movement for 12 hours is fetal alarm signal…Call provider immediately!
Biophysical Assessment cont’d
____________ - Fetal well-being
⚬ Indications for use
■ Fetal heart rate activity – (as of 6 wks)
■ Gestational age
■ Fetal growth – (IUGR)
■ Fetal anatomy
■ Fetal genetic disorders –nuchal translucency (NT)
■ Placental position and function – (migration up from early pregnancy)
■ Adjunct to other invasive tests – amniocentesis, version, others
⚬ Amniotic Fluid Volume
■ Oligohydramnios - decreased fluid
■ Polyhydramnios - increased fluid
Ultrasonography - Fetal well-being
⚬ Indications for use
■ Fetal heart rate activity – (as of 6 wks)
■ Gestational age
■ Fetal growth – (IUGR)
■ Fetal anatomy
■ Fetal genetic disorders –nuchal translucency (NT)
■ Placental position and function – (migration up from early pregnancy)
■ Adjunct to other invasive tests – amniocentesis, version, others
⚬ Amniotic Fluid Volume
■ Oligohydramnios - decreased fluid
■ Polyhydramnios - increased fluid
- Ultrasonography cont’d
⚬ Biophysical Profile (BPP)
■ Real-time detailed assessment of physical and ________ characteristics
■ Noninvasive dynamic assessment based on acute/chronic markers
⚬ Modified Biophysical Profile
■ Combines nonstress test, which assesses the current fetal condition, with measurement of the quantity of amniotic fluid, an indicator of placental function over a longer period of time
■ ___________ volume determined by measuring a single deepest pocket of fluid instead of using the AFI (amniotic fluid index).
■ Desired test results are a reactive nonstress test and a single deepest vertical pocket of amniotic fluid that is more than 2 cm (Wilson 233)
⚬ Nursing role
■ Counseling and education regarding the procedure
⚬ Biophysical Profile (BPP)
■ Real-time detailed assessment of physical and physiologic characteristics
■ Noninvasive dynamic assessment based on acute/chronic markers
⚬ Modified Biophysical Profile
■ Combines nonstress test, which assesses the current fetal condition, with measurement of the quantity of amniotic fluid, an indicator of placental function over a longer period of time
■ Amniotic fluid volume determined by measuring a single deepest pocket of fluid instead of using the AFI (amniotic fluid index).
■ Desired test results are a reactive nonstress test and a single deepest vertical pocket of amniotic fluid that is more than 2 cm (Wilson 233)
⚬ Nursing role
■ Counseling and education regarding the procedure
Biochemical Assessment
Chorionic villus sampling (CVS)
⚬ Earlier diagnosis and rapid results
⚬ Performed between 10 and 13 weeks of gestation
⚬ Removal of small ______ specimen from fetal portion of placenta (chorionic villi)
■ Can detect __________ defections but not the severity
■ Does not detect neural tube defects
■ Higher incidence of miscarriage and pain
Chorionic villus sampling (CVS)
⚬ Earlier diagnosis and rapid results
⚬ Performed between 10 and 13 weeks of gestation
⚬ Removal of small tissue specimen from fetal portion of placenta (chorionic villi)
■ Can detect chromosomal defections but not the severity
■ Does not detect neural tube defects
■ Higher incidence of miscarriage and pain
Biochemical Assessment
Amniocentesis
⚬ 14-20 weeks
⚬ Indication for use
■ ________ concerns - Women over 35 years old, family history of ___________ abnormalities
■ Can detect chromosomal issues and neural tube defects
■ Pulmonary maturity
* L/S lecithin–sphingomyelin ratio
* and S/A** ratios
■ Risk of miscarriage, infection, Rh isoimmunization, rupture of membranes, labor
Amniocentesis
⚬ 14-20 weeks
⚬ Indication for use
■ Genetic concerns - Women over 35 years old, family history of chromosomal abnormalities
■ Can detect chromosomal issues and neural tube defects
■ Pulmonary maturity
* L/S lecithin–sphingomyelin ratio
* and S/A** ratios
■ Risk of miscarriage, infection, Rh isoimmunization, rupture of membranes, labor
Biochemical Assessment cont’d
- Percutaneous _______ blood sampling (PUBS)
⚬ _____ocentesis - direct access to fetal circulation during 2nd/3rd trimester
⚬ For fetal blood sampling and transfusion
- Percutaneous umbilical blood sampling (PUBS)
⚬ Cordocentesis - direct access to fetal circulation during 2nd/3rd trimester
⚬ For fetal blood sampling and transfusion
Antepartum Assessment Using Electronic Fetal Monitoring
- Goal ⚬ Determine if the intrauterine environment is supportive to the fetus
■ ______ trimester - Indications
⚬ Diabetes, hypertension, intrauterine growth restriction, multiple gestation, oligohydramnios, decreased fetal movement, postterm pregnancy….
- Goal ⚬ Determine if the intrauterine environment is supportive to the fetus
■ Third trimester - Indications
⚬ Diabetes, hypertension, intrauterine growth restriction, multiple gestation, oligohydramnios, decreased fetal movement, postterm pregnancy….
Antepartum Assessment Using Electronic Fetal Monitoring cont’d
- Nonstress Test (NST)
⚬ FHR response to fetal activity
⚬ Procedure – external monitor
⚬ Interpretation
■ Reactive test: ____ accelerations in a ____-minute period, each lasting at least 15 seconds and peaking at least ___ beats/min above the baseline. (Before 32 weeks of gestation, an acceleration is defined as a rise of at least 10 beats/min lasting at least 10 seconds from onset to offset)
■ Nonreactive test: A test that does not demonstrate at least ____ qualifying accelerations within a ___ -minute window
- Nonstress Test (NST)
⚬ FHR response to fetal activity
⚬ Procedure – external monitor
⚬ Interpretation
■ Reactive test: Two accelerations in a 20-minute period, each lasting at least 15 seconds and peaking at least 15 beats/min above the baseline. (Before 32 weeks of gestation, an acceleration is defined as a rise of at least 10 beats/min lasting at least 10 seconds from onset to offset)
■ Nonreactive test: A test that does not demonstrate at least two qualifying accelerations within a 20-minute window
Antepartum Assessment Using Electronic Fetal Monitoring cont’d
- ___________ Stimulation (VAS)
⚬ Fetal acoustic stimulation test (FAST)
⚬ Performed in conjunction with NST
⚬ Procedure - uses sound and vibration to stimulate fetus
- Vibroacoustic Stimulation (VAS)
⚬ Fetal acoustic stimulation test (FAST)
⚬ Performed in conjunction with NST
⚬ Procedure - uses sound and vibration to stimulate fetus
Antepartum Assessment Using Electronic Fetal Monitoring cont’d
- Contraction Stress Test (CST) - rarely done now
⚬ Oxytocin Challenge Test (OCT)
⚬ Procedure
■ Nipple-stimulated contraction test
■ Oxytocin-stimulated contraction test
■ Achieve __ or more contractions in a 10 minute window
■ Provides a warning of fetal compromise earlier than NST
⚬ Interpretation - ACOG
■ Negative - no late or significant variable decelerations
■ Positive - late decelerations following > 50% of contractions
■ Equivocal
* Suspicious - intermittent late decelerations or significant variable decelerations
* Hyperstimulatory - decelerations in presence of UCs > q 2 minutes or >90 seconds
■ Unsatisfactory - < 3 UCs in 10 minutes or tracing not interpretable
- Contraction Stress Test (CST) - rarely done now
⚬ Oxytocin Challenge Test (OCT)
⚬ Procedure
■ Nipple-stimulated contraction test
■ Oxytocin-stimulated contraction test
■ Achieve 3 or more contractions in a 10 minute window
■ Provides a warning of fetal compromise earlier than NST
⚬ Interpretation - ACOG
■ Negative - no late or significant variable decelerations
■ Positive - late decelerations following > 50% of contractions
■ Equivocal
* Suspicious - intermittent late decelerations or significant variable decelerations
* Hyperstimulatory - decelerations in presence of UCs > q 2 minutes or >90 seconds
■ Unsatisfactory - < 3 UCs in 10 minutes or tracing not interpretable
Metabolic Disorders
- Diabetes mellitus
⚬ Most common __________ disorder associated with pregnancy
⚬ Pregnancy complicated by diabetes considered ________
⚬ Can be successfully managed with a multidisciplinary approach
⚬ Key to an optimal outcome is strict maternal ________ control
- Diabetes mellitus
⚬ Most common endocrine disorder associated with pregnancy
⚬ Pregnancy complicated by diabetes considered high risk
⚬ Can be successfully managed with a multidisciplinary approach
⚬ Key to an optimal outcome is strict maternal glucose control
⚬ Classification of diabetes
■ Type 1 - absolute insulin ___________
■ Type 2 - insulin ___________
■ Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or recognition during pregnancy, but typically diagnosed after ___ weeks gestation
■ Type 1 - absolute insulin deficiency
■ Type 2 - insulin resistance
■ Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or recognition during pregnancy, but typically diagnosed after 20 weeks gestation
Diabetes
⚬ Pathogenesis
■ Group of metabolic diseases characterized by ____________ resulting from defects in _________ secretion, _________ action or both
⚬ Pathogenesis
■ Group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both
Metabolic Disorders cont’d * Glucose Metabolism in Pregnancy
⚬ Normal pregnancy – progressive insulin resistance
⚬ Weeks 1- 8
■ ______ increase in resistance R/T human chorionic gonadotropin (HCG) and progesterone
⚬ Weeks 9 – 15
■ Estrogen and progesterone increase as placenta established
⚬ Stimulates hyperplasia of pancreas islet cells -> ______ insulin production and tissue sensitivity to insulin
⚬ Weeks 16 – 25
■ ______ in insulin blocking hormones as placenta grows
* Insures adequate transport of glucose to fetus (Human chorionic somatotropin,
human placental lactogen, prolactin)
■ By 24 weeks pancreas needs to secrete twice the pre-pregnancy insulin to maintain
normal blood glucose level
⚬ Weeks 1- 8
■ Slight increase in resistance R/T human chorionic gonadotropin (HCG) and progesterone
⚬ Weeks 9 – 15
■ Estrogen and progesterone increase as placenta established
⚬ Stimulates hyperplasia of pancreas islet cells -> increased insulin production and tissue sensitivity to insulin
⚬ Weeks 16 – 25
■ Increase in insulin blocking hormones as placenta grows
* Insures adequate transport of glucose to fetus (Human chorionic somatotropin,
human placental lactogen, prolactin)
■ By 24 weeks pancreas needs to secrete twice the pre-pregnancy insulin to maintain
normal blood glucose level
Metabolic Disorders cont’d - Glucose Metabolism in Pregnancy cont’d
⚬ Week 26 – 35
■ Endogenous insulin requirement _________
⚬ Week 36 +
■ Requirement levels off
⚬ Diabetes during pregnancy
■ Unable to double or triple their insulin secretion -> can’t overcome insulin blocking effects of placental hormones -> ___________ blood glucose levels
⚬ Week 26 – 35
■ Endogenous insulin requirement triples
⚬ Week 36 +
■ Requirement levels off
⚬ Diabetes during pregnancy
■ Unable to double or triple their insulin secretion -> can’t overcome insulin blocking effects of placental hormones -> elevated blood glucose levels
Metabolic Disorders cont’d
- Pregestational diabetes mellitus (Type 1 or 2)
⚬ Preconception counseling-
⚬ Key goal is to get blood glucose levels under control ________ and in early pregnancy.
⚬ Congenital defects related to diabetes is more likely in _____ pregnancy.
⚬ May need adjustment on medication. Most pregnant women requiring medication will need to be on _________
⚬ Preconception counseling-
⚬ Key goal is to get blood glucose levels under control before and in early pregnancy.
⚬ Congenital defects related to diabetes is more likely in early pregnancy.
⚬ May need adjustment on medication. Most pregnant women requiring medication will need to be on insulin
Metabolic Disorders cont’d
⚬ Maternal risks and complications
■ Macrosomia
■ Hydramnios/Polyhydramnios
■ Ketoacidosis
■ Hyperglycemia
■ Hypoglycemia
⚬ Fetal and neonatal risks
■ Sudden and unexplained stillbirth
■ Congenital malformations
■ Respiratory distress
■ Hypo/hyperglycemia
■ SGA/IUGR
■ LGA/Macrosomia
⚬ Maternal risks and complications
■ Macrosomia
■ Hydramnios/Polyhydramnios
■ Ketoacidosis
■ Hyperglycemia
■ Hypoglycemia
⚬ Fetal and neonatal risks
■ Sudden and unexplained stillbirth
■ Congenital malformations
■ Respiratory distress
■ Hypo/hyperglycemia
■ SGA/IUGR
■ LGA/Macrosomia
- Gestational diabetes mellitus (GDM)
⚬ Diagnosed during __________ of pregnancy
⚬ Maternal-fetal risks
⚬ Screening for gestational diabetes mellitus
■ One and two step screening
⚬ Diagnosed during 2nd half of pregnancy
⚬ Maternal-fetal risks
⚬ Screening for gestational diabetes mellitus
■ One and two step screening
Metabolic Disorders cont’d - * DM care management
⚬ Antepartum evaluation
■ Interview
■ Physical examination
■ Laboratory tests
- Baseline renal function
⚬ ____ urine collection - total protein excretion and creatinine clearance - UA and culture
- Thyroid
- Glycosylated hemoglobin A1C
■ Patient needs much more frequent monitoring
⚬ Antepartum evaluation
■ Interview
■ Physical examination
■ Laboratory tests
- Baseline renal function
⚬ 24-hr urine collection - total protein excretion and creatinine clearance - UA and culture
- Thyroid
- Glycosylated hemoglobin A1C
■ Patient needs much more frequent monitoring
Metabolic Disorders cont’d * DM care management cont’d
⚬ Antepartum care
■ Diet
■ __________ - 30-60 min daily
■ Insulin therapy
■ Monitoring blood glucose levels
* ___ times/day
* Continuous glucose monitoring (GCM)
■ Urine testing
■ Complications requiring hospitalization
■ Fetal surveillance
* NST weekly or biweekly starting 28 or 32 weeks gestation
■ Determination of birth date and mode of birth, often delivered before 39 weeks
⚬ Antepartum care
■ Diet
■ Exercise - 30-60 min daily
■ Insulin therapy
■ Monitoring blood glucose levels
* 4-8 times/day
* Continuous glucose monitoring (GCM)
■ Urine testing
■ Complications requiring hospitalization
■ Fetal surveillance
* NST weekly or biweekly starting 28 or 32 weeks gestation
■ Determination of birth date and mode of birth, often delivered before 39 weeks