Week 4 Conception and Prenatal Development Flashcards

1
Q

When is the preembryonic peroid?

A

The first two weeks after conception

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2
Q

The fertilized ovum is considered a ____ after the 4th day and enters the ___

A

Zygote

uterus

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3
Q

When the zygote divides into 16 cells it is considered a ___

A

Morula

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4
Q

What stage comes after the morula? how is this formed?

A

the blastocyst. The outter cells of the morula secrete fluids that divide the morula into and inner and outer cell mass

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5
Q

How does the zygote maintain itself in the uterus

A

It moves to the uterus during the secretory phase of the mestral cycle
-it then releases hormones that signal pregnancy and the uterus stays in this phases allowing for more nutrients and blood flow

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6
Q

what hormone is released by the conceptus that causes the corpus luteum to persist?

A

human chorionic gonadotropin

hCG

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7
Q

Why is the site of implantation important?

A

Because it is where the placenta develops

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8
Q

Where does normal implantation occur?

A

the upper uterus

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9
Q

Why is the upper uterus the ideal place for implantation?

A
  • Rich supply of blood
  • Think lining
  • limits blood loss after birth
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10
Q

Explain the mechanism of implantation

A

the conceptus produces corrosive enzymes that erode the decidua
-chorionic villi project into the surface of the decidua

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11
Q

How many days after fertilization does implantation fully occur?

A

10days

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12
Q

What is a common reason for women to think they are not pregnant during the time of their next mestral period after conception?

A

The implantation of the concepus may cause a small amount of spotting that can be confused with a normal menstral period

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13
Q

When does the embryonic period start/end?

A

Beginning of the third week through the eight wek after conception

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14
Q

What occurs duing the embryonic period?

A

Basic structures of all major body organs are completed and are in place

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15
Q

When is the fetus most vulnerable for teratogens? Why is this?

A

-The embryonic period
Because all the major body systems are developing at a rapid rate. If one system is affected by a teratogen than it can cascade and cause a multi system issue

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16
Q

Explain the direction of growth during the embryonic stage

A
  • Cephalocaudal
  • Central-to-peripheral
  • simple to complex
  • General to specific
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17
Q

An infant if considered full term __ weeks after conception and ___ weeks after last menstrual period

A

36-40

38-42

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18
Q

Most women miss their period after __ weeks

A

3

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19
Q

Describe the neural tube at 3 weeks?

A

Open at both ends

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20
Q

When does the primitive/tubular heart begin beating?

A

22-23 days

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21
Q

When does the neural tube close?

A

during the 4th week

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22
Q

What happens if the neural tube does not close?

A

defects such as anencephaly and spinal bifida results

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23
Q

The cranial end of the neural tube forms the ___ and the caudal end forms the ___

A

Brain

Spinal cord

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24
Q

When does the infant heart develop its 4 chambers and begin beating?

A

during the 4th week

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25
Q

During what period in fetal development is the fetus at risk for developing a neural type defect?

A

The embryonic period because the neural tube is still open n the earlier weeks of this stage

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26
Q

When does the pituitary gland a cranial nerves develop?

A

Week 6

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27
Q

why is the head sharply flexed during week 6?

A

Rapid brain growth

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28
Q

Describe the spinal cord during week 8

A

It stops at the end of the vertebral column

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29
Q

When is the heart beat first detectable via ultrasound?

A

week 8

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30
Q

When does the fetal period start/end?

A

Weeks 9-birth

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31
Q

When does the fetal digestive tract become patent?

A

week 10

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32
Q

When should a fetal heart beat be detectable by doppler transducer?

A

week 12

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33
Q

When does the sucking reflex begin?

A

week 12

34
Q

When do the fetal kidneys begin producing urine?

A

week 12

35
Q

When does lanugo begin to develop?

A

week 12

36
Q

When is the fetal face “human looking”

A

week 16

37
Q

When does the fetus begin to excrete urine into the AF

A

week 16

38
Q

when does the fetus produce its first meconium. What is the food source?

A

week 16

swallows AF

39
Q

When should a woman who has been pregnant before begin to feel fetal movements?
What is this called

A

week 16

-quickening

40
Q

When is the fetal heart beat detectable using a regular fetoscope?

A

week 20

41
Q

When are fetal movements often felt by all mothers and experienced examiners?

A

week 20

42
Q

When is brown fat production complete?

A

week 20

43
Q

When does surfactant production begin?

A

week 20

44
Q

When do surfactant levels become high enough to support life

A

26-28 weeks after conception

45
Q

When does surfactant production reach its peak?

A

the last 2 weeks of preg

46
Q

When is the earliest survivable birth?

A

24 weeks

47
Q

When is the fetus considered active?

A

24 weeks

48
Q

When do fetal movements become progressively more noticeable?

A

24 weeks

49
Q

When does the CNS mature?

A

weeks 25-28

50
Q

When do the lungs mature?

A

weeks 25-28

51
Q

When do the pulmonary capillaries mature?

A

Week 25-28

52
Q

When does the fetus assume a head down positon?

Why?

A

Weeks 25-28

-Because the uterus is shaped like an inverted egg and the fetal head is heavy and gravity pulls it down

53
Q

When does surfactant reach near mature levels?

A

week 32

54
Q

When are the sympathetic and para-sympathetic NS near maturity?

A

Weeks 29-32

55
Q

With the maturation of the sym and para-sym nervous systems, what occurs? When does this occur?

A

Variability on the EFM

-weeks 29-32

56
Q

when is the pulmonary system matured enough to enable efficient and unlabored breathing?

A

weeks 33-38

57
Q

Where does the exchange of substances between mother and baby occur?

A

the intervillous space

58
Q

How much of the mothers blood is in the intervillious space?

A

150ml

59
Q

What is the circulation rate of the intervillous space?

A

450-750 ml per minute

60
Q

The decidua contains ___ to ___ spiral arteries

A

80-100

61
Q

What is the key function of the placenta?

A

Respiration

62
Q

How does oxygen and carbon dioxide pass through the placenta?

A

diffusion

63
Q

What are the three reasons the fetus can survive in such a low O2 environment?

A
  1. Fetal Hgb is 20-50% mor efficent
  2. fetal blood has more hgb
  3. Hbg is more efficent at lower levels of CO2. Fetal blood entering the placenta is higher in CO2 and diffuses rapidly out of the placent into the mother blood stream. This makes the fetal blood alkaline and more efficent at absorbing O2
64
Q

What 4 nutrient types can pass directly across the placenta?

A

Glucose, fatty acids, vitamins, and elecrtolytes

65
Q

What is the major fuel source for fetal growth and metabolic activities?

A

Glucose

66
Q

Why are infant metabolic defects often not detected until after delivery?

A

Because the placenta removes wasts from the fetal blood stream, causing the waste buildup to only happen after the placenta is no longer a player

67
Q

What antibodies pass the placenta?

A

IgG

68
Q

What are the three main hormones produced by the placenta?

A
  • Estrogen
  • Progesterone
  • Human Placental Lactogen
69
Q

What is the function of Human Placental Lactogen?

A
  • Promotes normal nutrition and growth of the fetus
  • Causes maternal breast development for lactation
  • Decrease maternal insulin sensitivity and glucose use (making more available for baby)
70
Q

What is the function of estrogen produced by the placenta?

A

-Enlargement of the mothers uterus, breasts, ductal systems, and external genitalia

71
Q

What is the function of pregesterone produced by the placenta?

A
  • Maintains uterine conditions for preg.
  • Modifies and maintains the endometrium to receive the conceptus and form the decidua
  • Reduces muscle contractions of the uterus to prevent spontaneous abortons
72
Q

What is the function of amniotic fluid?

A

Protection of the fetus and promotion of normal development

73
Q

How does AF protect the fetus?

A
  • Cushioning against impacts

- Maintains temp

74
Q

How does AF promote normal development?

A
  • Allows symmetric development
  • Prevents membranes from adhering to developmental fetal parts
  • Allows room and buoyancy for fetal movements
75
Q

What is Oligohydramnios?

A

An abnormally small quantity of AF (less than 50% expected or under 400mL at term)

76
Q

What is a normal approx amount of AF at term?

A

700-800ml

77
Q

What are some causes of Oligohydramnios?

A
  • Poor placental perfusion
  • PPROM
  • Poor fetal kidney development
  • Blocked urinary excretion
  • Poor fetal lung development
  • Malformations from fetal compression
78
Q

What is polyhydraminos?

A

AF exceeding 200ml

79
Q

What are some causes of polyhydraminos?

A
  • Imblanaced water exchange of an unknown cause
  • Poorly controlled maternal DM resulting on fetal polyuria
  • Malformations of the CNS, CV, or Gi tract that interfere with ingestion, metabolism, or excretion
  • chromosomal abnormalities
  • Multifetal gestation
80
Q

Why has multifetal pregnancies increased in the US?

A

Increasing maternal age

81
Q

What are the two types of twins?

A

Monozygomatic

Dizygotic