Week 4: Basal Ganglia, Cerebellum, Cranial Nerve Pathways Flashcards
Parts of the Basal Ganglia
Striatum, Lenticular Nucleus, Substantia Nigra, Subthalamic Nucleus
Parts of the Striatum
Putamen, Nucleus Accumbens, Caudate Nucleus
Parts of the Lenticular Nucleus
Putamen, Globus Pallidus
Parkinson’s Disease Cause
Lack of dopamine in the substantia nigra
Parkinson’s Disease Symptoms
Resting tremors, cogwheel rigidity, shuffling gait
Hyperkinetic Disorders
Hemiballismus, Huntington’s Disease
Region Affected in Hemiballismus
Subthalamic Nucleus
Hemiballismus Symptoms
Violent Involuntary Movement of Proximal Limbs
Region Affected in Huntington’s Disease
Striatum
Huntington’s Disease Symptoms
Dancing movements of distal limbs
Functional Divisions of Cerebellum
Spinocerebellum, Cerebrocerebellum, Vestibulocerebellum
Parts of Spinocerebellum
Vermis and paravermis
Parts of Cerebrocerebellum
Lateral Hemispheres
Parts of Vestibulocerebellum
Flocculonodular Lobe
Spinocerebellum Function
Postural and movement control of trunk and limbs
Cerebrocerebellum Function
Fine motor and nonmotor planning
Vestibulocerebellum Function
Coordinating head and eye movements
Deep Cerebellar Nuclei
Dentate, Emboliform and Globose, Fastigial
Dentate Nucleus Function
Relay Center of cerebrocerebellum to motor centers
Emboliform and Globose Nuclei Functions
Relay nuclei of the spinocerebellum to motor centers
Fastigial Nucleus Function
Project to Reticular Formations and Vestibular nuclei
Function of Cerebellar Peduncles
Moves information in and out of the cerebellum
Spinocerebellum Input Tracts from Lower Extremities and Trunk
Dorsal Spinocerebellar and Double Cross Ventral Spinocerebellar
Spinocerebellum Input Tracts from Upper Extremities
Cuneucerebellar, Double Cross Rostral Spinocerebellar
Spinocerebellar Fastigial Output Tract Destination
To reticular formation and reticulospinal tract, and vestibular nuclei and vestibulospinal Tract
Spinocerebellar Interposed Output Tract Destination
To red nucleus and ventrolateral nucleus of thalamus
Vestibulocerebellar Input
Directly from vestibular afferents and from vestibular nuclei
Vestibulocerebellar Output
Medial longitudinal fasciculus coordinating eye movement, medial vestibulospinal tract coordinating neck movement with eyes, lateral vestibulospinal tract maintaining balance
Cerebrocerebellar Input
Corticopontine fibers pontine nuclei pontocerebellar tract to contralateral cerebellum, corticorubroolivary path to olivocerebellar tract
Cerebrocerebellar Output
Dentathalamic fibers to ventrolateral nucleus of thalamus, fibers to red nucleus form loop through inferior olivary nucleus
Cerebellar Cell Layers Superficial to Deep
Molecular, Purkinje, Granule Cell
Granule Cell Layer Input
All pathways BUT the inferior olive
Mossy Fiber Input
Inferior olive
Purkinje Cell Input
Contralateral inferior olive and granule cells
Purkinje Cell Output
Deep Nuclei
Vestibulocerebellar Lesion
Wide gate and nystagmus
Spinocerebellar Lesion
Ataxia, stomping gate
Cerebrocerebellar Lesion
intention tremor, dysdiadochokinesia
Oculomotor and Edinger Westphal Nuclei Cranial Nerve and Location
CN III, rostral midbrain at level of red nucleus and superior colliculus
Oculomotor and Edinger Westphal Nuclei Blood Supply
paramedian branches from basilar and posterior cerebral arteries
Medial Logitudinal Fasiculus Function
Connects oculomotor nucleus top the nuclei of CN IV and VI
Trochlear Nucleus Location
Caudal midbrain where CN IV fibers cross to contralateral side
Trochlear Nucleus Blood Supply
paramedian branches from basilar and posterior cerebral arteries
Trigeminal Motor Nucleus Location
Medial to principle sensory nucleus of pons
Trigeminal Motor Nucleus Blood Supply
anterior inferior cerebellar or circumferential branches of basilar artery
Abducens Nucleus Blood Supply
Dorsal aspect of caudal pons surrounded by fibers of facial nerve to form facial colliculus
Abducens Nucleus Blood Supply
Paramedian branches of basilar
Facial Nucleus Location
Ventral Area of Tegmentum in caudal pons
Facial Nucleus Blood Supply
Anterior inferior cerebellar or circumferential branches of basilar
Superior Salivatory Nucleus of Facial Nerve Location
Dorsomedial to facial nucleus in mid to caudal pons
Nucleus ambiguus and Inferior Salivatory Nucleus Cranial Nerves and Location
CN IX, X, and XI in mid to central portion of rostral medulla
Nucleus ambiguus and Inferior Salivatory Nucleus Blood Supply
Posterior inferior cerebellar artery
Dorsal Motor Nucleus of Vagus Location
Rostral medulla deep to vagal trigone
Dorsal Motor Nucleus of Vagus Blood Supply
Posterior inferior cerebellar artery
Accessory Nucleus Location
Ventral horn of upper cervical cord
Accessory Nucleus Blood Supply
Posterior inferior cerebellar artery OR vertebral artery
Hypoglossal Nucleus Location
Rostral medulla deep to hypoglossal trigone where axons pass ventrally to emerge in the preolivary nucleus
Hypoglossal Nucleus Blood Supply
Anterior Spinal Artery or vertebral artery