week 4 Flashcards
peripheral artery disease
NARROWING of lower extremity arteries for atherosclerosis = inadequate blood flow
peripheral artery disease manifestations
pain at rest (aka intermittent clausication)
parethesia
bruit of femoral & aortic arteries
pallor
dependent rubor
cool extremities
nonpalpable peripheral pulses
calf muscle atrophy
shiny skin w hair loss & thick toenails
6P’s manifestations of acute occlusion from thrombosis
Pain
Pallor
Paralysis
Parethesia
Pulselessness
Poikilothermia (cant regulate temp)
lab values indicating risk for peripheral arterial disease
elevated:
*c-reactive protein
*homocysteine level
* lipids— hyperlipidemia
PAD manifestations commonly occur
**aggravated by limb elevation
occurs @ night
@ rest
diagnostic studies for PAD
- Ankle-Brachial Index <0.9
- 6min walk test
- doppler ultrasound
- Segmental systolic BP measurements
- Peripheral vascular angiography
meds for intermittent claudication
**pain @ rest w PAD
- Cilostazol
- Pentoxifylline
- Statins
med to increase blood flow
*PAD = ramipril
*risk for hyperkalemia –muscle weakness, paralysis, abdominal cramps
PAD complications
- ulcers
- wounds
- compartment syndrome
- infection
- amputation
Buerger’s disease
*THROMBOANGIITIS OBLITERANS
recurring inflammation of the arteries & veins resulting in THROMBOSIS w OCCLUSION
** men 20 - 35yrs old **
Buerger’s disease risk factors
genetics
smoking
tobacco
men: 20 to 35yrs old
Buerger’s manifestations
painful open sores
ulcers w gangrene
claudication
cold sensitivity
nursing care for buerger’s
- smoking cessation
- avoid cold & constrictive clothing
- pain meds
- antibiotics
Raynaud’s Syndrome
EPISODIC vasospastic disorder of arteries/arterioles cold & stress
manifestations of Raynaud’s Syndrome
2 phases
- Vasoconstrictive phase = cold/white extremities w pain
- Hyperemic phase = blood flow to extremities (red & swelling)
nursing care for Raynaud’s
- avoid cold & keep warm
- stop smoking
- limit caffeine
- manage stress
Virchow’s triad
presence of 3 factors predisposes a person to develop vascular thrombosis
(1) hypercoagulability
(2) venous stasis
(3) endothelial damage
Risk factors for venous thromboembolisms
surgery / immobility
oral contraceptives
65+
pregnancy
obesity
catheters
clinical manifestations of venous thromboembolisms
asymptomatic
calf/groin tenderness
warm, erythematous skin
change in circumference of extremity
diagnostic studies for VTE
D-dimer
ultrasound
CT / MRI
CT pulmonary angiography
V/Q scan
antidote for heparin
protamine sulfate
white clot syndrome
antibody development to a heparin-platelet membrane complex
*arterial thrombi
enoxaparin
SubQ low-molecular weight heparin
1mg/kg of body weight not to exceeed 90mg BID
antidote for warfarin
Vitamin K
3 IV thrombolytics & monitoring for…
Reteplase
tenecteplase
activase (tPA)
*neuro status
bleeding
anaphylaxis
Intracranial bleeding
Dabigatran
PO direct thrombin inhibitor
antidote= idarucizumab