Week 3 Respiratory Tract Infections ✅ Flashcards

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1
Q

What is the shape of mycoplasma and why?

A

No shape as no cell wall

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2
Q

What are examples of secondary invaders?

A

Strep pyogenes
Strep pneumoniae

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3
Q

What are examples of professional invaders?

A

Influenza (Strep pyogenes/strep pneuomiae)
TB
Bordetella pertussis
Rhinovirus

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4
Q

How are viruses normally diagnosed?

A

Clinical presentation

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5
Q

What kind of drugs can treat viruses?

A

Antiherpetic
Antiretroviral

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6
Q

What is nasopharyngitis?

A

Rhinitis + pharyngitis + fever

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7
Q

What viruses cause the common cold?

A

Rhinovirus
Coronavirus
Influenza
Parainfluenza

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8
Q

Why is rhinovirus not systemic?

A

Replication 33’c

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9
Q

What can cause pharyngitis/tonsilitis?

A

Common cold virus
Coxsackie virus A (herpangia)
EBV
HSV
Strep pyogenes
Neisseria gonorrhoea
Mycoplasma pneumoniae

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10
Q

What type of bacteria is streptococcus?

A

Gram positive ovococci - chains of pearls

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11
Q

What is group A strep?

A

Strep pyogenes

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12
Q

Why must Strep A be treated ASAP?

A

Can return as rheumatic fever

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13
Q

What is group B strep?

A

Strep agalactiae

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14
Q

What is EBV?

A

Epstein-Barr Virus

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15
Q

What are the symptoms of EBV?

A

Soft palate petechiae, exhaustion, jaundice, entire neck swollen

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16
Q

What is a complication of EBV?

A

Burkitt’s lymphoma

17
Q

What are the usual causes of pneumonia in children vs adults?

A

Children - virus
Adults - bacteria

18
Q

What are risk factors for pneumonia?

A

Age
Influenza primary infection which leads to secondary bacterial pneumonia

19
Q

What is a screening tool for hospitalisation for pneumonia?

A

CRB65

20
Q

How can pneumonia be diagnosed?

A

CPR
Sputum macro, micro, culture and sensitivity
CXR
PCR

Urine antigen test for pneumococcus legionella
Fluid sampling from lung
(HAP)

21
Q

What diseases can cross lung fissures?

A

TB
Fungal diseases

22
Q

What are the most common bacteria to cause pneumonia?

A

Strep pneumoniae
Haemophilus influenza

23
Q

What are atypical bacterial causes of pneumonia?

A

Mycoplasma pneumoniae
Legionella pneumonphilia
S aurus

24
Q

Which viruses can cause pneumonia?

A

RSV
Influenza
Mumps
ZVZ

25
Q

Which fungi can cause pneumonia?

A

Candida, Toxoplasma

26
Q

Which pathogens grow so slowly they can evade the immune system?

A

TB
Syphillis

27
Q

Which is more aggressive, CAP or HAP?

A

CAP because HAP affects immunocompromised patients

28
Q

What is another name for orthomyxovirus?

A

Influenza

29
Q

How does influenza affect host cells?

A

Hemagglutinin binds to sialic acid on host cells

Neuraminidase from virus destroys sailic acid

30
Q

What is an example of a neuraminidase inhibitor?

A

Zanamivir

31
Q

What is an example of genetic shuffling?

A

Influenza A antigenic shift to new influenza A subtype

32
Q

What is an example of random mutation?

A

Antigenic shift of Influenza A to different strains

33
Q

What usually causes bronchitis?

A

Viruses