Week 3 - Oral Manifestations of GI Disease

Question 1

dental erosion: NCTSL
pH of stomach can go as low as?
erosion usually occurs on which teeth?
which diseases usually present erosion?
what kind of causes can there be?

Answer 1

• pH 1
• palatal surface of upper anterior teeth
• GORD, and also bulimia
• may have dietary cause or from previous problem

Question 2

patients with GI cancers have increased risk of what other cancer?

Answer 2

mouth cancer

Question 3

non-specific oral signs and symptoms of GI disease?

Answer 3

• angular cheilitis
• burning mouth syndrome
• candidal infections
• recurrent oral ulceration

Question 4

iron:
where in diet?
where absorbed? can be aided by?
one drink that can interfere with iron absorption?
who becomes deficient?

Answer 4

• read meat, leafy veg, raisin/apricots
• absorbed in duodenum
• aided by vitamin C
• tea
• pre-menopausal women: blood loss through menstruation
• post-menopause & in men: loss of blood in GI tract or malabsorption (coeliac disease), helicobacter infection

Question 5

vitamin B12:
where in diet?
where absorbed?
who becomes deficient?

Answer 5

• exclusively from meat or dairy produce
• absorbed in distal ileum
• vegans susceptible, those with pernicious anaemia as well, due to the insufficient level of intrinsic factor, which aids B12 absorption

Question 6

folate:
where in diet?
how absorbed?
who becomes deficient?

Answer 6

• green leafy veg, broccoli, brussel sprouts, chickpeas, brown rice
• absorbed in jejunum
• those with crohn’s disease or coeliac disease, due to malabsorption

Question 7

coeliac disease:
those affected can be deficient in?
which villi affected? 
how many people in a population affected?
why is it important to diagnose?

Answer 7

• iron, folate and even B12
• jejunal villi affected
• 1 in 250 affected
• increased development of osteoporosis

Question 8

crohn’s disease:

oral manifestations?

Answer 8

• ulcers
• facial/labial swelling
• mucosal tags
• cobblestone mucosa
• angular cheilitis

Question 9

ulcerative colitis:
oral manifestations: how common?
what are some possibilities?

Answer 9

• oral manifestations rare
• ulcers
• pyostomatitis vegetans
• lesions related to anaemia