Week 1 - Cardiovascular Disease I Flashcards
what is the most important disease process in the developed world?
atherosclerosis
atherosclerosis can appear in which 4 diseases?
- ischaemic heart disease
- peripheral vascular disease
- cerebrovascular disease
- renovascular disease
atherosclerosis: describe the basic pathology and what 2 things the disease results from
- accumulation of lipid rich plaques in arterial walls
disease results from:
- progressive narrowing; reduction of blood supply leading to ischaemia
- plaque rupture leading to thrombus formation and occlusion of blood supply -> infarction
what are the big 5 risk factors for atherosclerosis
smoking high cholesterol high blood pressure diabetes genes
risk factors: smoking
what should healthcare workers advise on?
- smoking prevention: dont start
- smoking management: advice, medication, acupuncture, hypnotism, group support
risk factors: smoking
what kind of medication can be given to patients to curb smoking?
- nicotine replacements
- pharmacological: buproprion (zyban)
risk factors: high cholesterol
caused by?
ways of management?
- lifestyle
- genetic contribution: familial hypercholesterolaemia
- dietary modifications
- drugs: statins
risk factors: hypertension
- BP stated as? describe each
- what are the figures that represent high BP? how does this value change?
- BP is the systolic / diastolic value
systolic: heart pumping
diastolic: heart relaxing - 160 / 90 is considered high BP
- value can change if pt has existing heart disease
risk factors: hypertension
- usually primary or secondary? can be related to?
secondary hypertension: how often? what 2 factors cause it?
- primary; no single underlying cause
- but related to:
- obesity, alcohol, high salt diet, genetics
- secondary hypertension is the minority, where there is an underlying cause
1. endocrine disease: hormonal excess
2. renal disease: kidneys not functioning well
risk factors; hypertension
symptoms?
if very high, 240/130, what are the symptoms?
- high BP is asymptomatic, unless extremely high
- fits
confusion
headache
breathlessness
chest pain
risk factors: hypertension
management?
- new referral to GP to rule out underlying causes and initiate treatment
- if untreated, postpone surgery that require anaesthetic until under control
- advice on lifestyle changes: lose weight, cut alcohol, low salt diet, exercise
risk factors: hypertension
what are the drugs used in management and their examples? x5
- B-blockers: bisoprolol, atenolol
- diuretics: bendroflumethiazide
- ACE inhibitors: ramipril
- angiotensin II antagonists: valsartan
- calcium channel blockers: amlodipine
risk factors: diabetes
- what is it
- how to improve atherosclerosis risk
- diabetes mellitus is elevated blood sugar
- control of blood sugar
risk factors: genetics
how to identify risk?
- from family history, calculate risk with SCORE system
- modify other risk factors
other risk factors for atherosclerosis?
obesity
lack of exercise
diet: low cholesterol, avoid excess, five a day