Week 3- Neoplasia Flashcards
Apoptosis
Programmed cell death that occurs naturally in the body as a way to eliminate damaged or unnecessary cells.
Metaplasia
A reversible change where one type of adult cell is replaced by another type, often as an adaptive response to chronic irritation or inflammation.
Hyperplasia
An increase in the number of cells in a tissue or organ, leading to its enlargement. It can be a normal or pathological process.
Neoplasia
he uncontrolled, abnormal growth of cells or tissues, which forms a neoplasm (tumour). This growth can be benign or malignant.
Tumour
An abnormal mass of tissue that results from excessive cell proliferation. Tumours can be benign (non-cancerous) or malignant (cancerous).
Malignancy
A term used to describe a cancerous tumor that has the ability to invade surrounding tissues and spread (metastasize) to other parts of the body.
Dysplasia
Abnormal development or growth of cells within a tissue, often considered precancerous. It can range from mild to severe.
Angiogenesis
The formation of new blood vessels from pre-existing ones, a process often co-opted by tumors to supply nutrients and oxygen for growth.
Homogenous vs heterogenous
Homogeneous: Consisting of cells or tissues that are uniform in structure or composition. Heterogeneous: Consisting of cells or tissues that are diverse or varied in structure or composition.
Invasion/ infiltrative
The ability of cancer cells to spread into surrounding tissues, breaking through normal tissue boundaries.
encapsulated
A tumour that is enclosed in a fibrous capsule, which may help prevent it from spreading to surrounding tissues.
Differentiated (highly/well- vs poorly/un-)
Highly/Well-Differentiated: Tumour cells that closely resemble normal cells in structure and function. Poorly/Un-Differentiated: Tumour cells that look and behave very differently from normal cells, often indicating a more aggressive cancer.
carcinoma-in-situ
A localized, non-invasive cancer that is confined to the layer of cells where it began and has not spread to surrounding tissues.
metastasis/metastasize.
The spread of cancer cells from the original tumour site to other parts of the body, forming secondary tumours.