Week 3 Drugs (Benadryl, Cardizem and Valium) Flashcards
Diazepam (Valium)
Pharmacology and Actions
- Benzodiazepine drug
- Decrease seizures by increasing seizure threshold
- Sedative
- Amnestic effect
Diltiazem (Cardizem)
Pharmacology and Actions
- Calcium Channel Blocker
- Inhibits cardiac conductions in AV node, slowing ventricular rate associated with A Fib and A Flutter
- Inhibits extracellular calcium ion influx, inhibiting contraction and dilating main coronary and systemic arteries
Diphenhydramine (Benadryl)
Pharmacology and Actions
- Histamine H-1 receptor agonist blocks histamine response in respiratory tract, blood vessels, and GI smooth muscle.
- Anticholinergic actions useful in treating or preventing acute dystonic rxn to antipsychotic drugs
Diazepam (Valium)
Indications
- Active seizures
- Sedation prior to cardiversion
Diltiazem (Cardizem)
Indications
- Narrow complex tacharrythmias: AFib/AFlutter
- SVT not responding to adenosine
Diphenhydramine (Benadryl)
Indications
- Treatment of allergic rxn
- Treatment or prevention of dystonic rxn to antipsychotic drugs
Diazepam (Valium)
Cantraindications
- Severe respiratory depression
- Allergy
Diltiazem (Cardizem)
Contraindications
- Heart block
- Bradycardia
- Systolic BP below 90 mmHg
- Sick sinus syndrome
- V Tach
- Allergy
Diphenhydramine (Benadryl)
Contraindications
- Newborns
- Hypersensitivity
- Allergy
Diazepam (Valium)
Precations and Side Effects
- Pt must be monitored closely for respiratory depression and hypotension
- Diazepam should not be given without a good IV in place and BVM ready
- Produces respiratory depression when given rapidly or in pts who have taken other depressants like barbituates and alcohol
- Use caution with administering further benzodiazapine to pts who received rectal dose prior to EMS arrival.
- Paradoxical excitement or stimulation may occur
Diltiazem (Cardizem)
Precautions and Side Effects
- Prolongnation of AV node conduction may result in 2nd or 3rd degree AV block
- Should not be administered to compromised myocardium (CHF, AMI, or cardiomyopathy)
- Use caution in hypotensive pts
Diphenhydramine (Benadryl)
Precautions and Side Effects
- Usually causes sedation
- May cause paradoxical excitation in children
- May have additive sedation effect with alcohol or other CNS depressants
- May cause hypotension when given IV/IO
Diazepam (Valium)
Administrtation
Route: IV Route: IM
Onset: 1-5 mins Onset: 15-30 mins
Peak Effect: 15 mins Peak Effect: 30-45 mins
Duration: 15-60 mins Duration: 15-60 mins
Diltiazem (Cardizem)
Administration
Route: IV/IO
Onset: 3 mins
Peak Effect: 7 mins
Duration: 1-3 hrs
Diphenhydramine (Benadryl)
Administration
Route: IV/IO
Onset: 10-15 mins
Peak Effect: 1 hour
Duration: 6-8 hours
