Week 1 Drugs (Adenosine, Ventolin, Amiodarone, Aspirin) Flashcards
Adenosine
Pharmacology and Actions
- Slows conduction through the AV node
- Most cases of PSVT involve AV nodal reentry, adenosine interrupts AV nodal circuit stopping tachycardia and restoring normal sinus rythm
Albuterol Sulfate
Pharmacology and Actions
- Beta-2 andrenergic bronchodilator
- Beta-2 agonist that relaxes bronchial smooth muscle, resulting in bronchial dilation
- Beta-1 overlap with clinically significant cardiac effects such as tachycardia
- Shift potassium intracellular, resulting in lower serum potassium
Amiodarone
Pharmacology and Actions
- Multiple effects on sodium, potassium and calcium channels
- Prolongs action potential and repolarization
- Decreases AV conduction and sinus node function
- Also has some alpa- and beta-adrenergic blocking properties
Aspirin
Pharmacology and Actions
- Inhibits prostaglandin and disrupts platelet function
- Mild analgesic and anti-inflammatory
Adenosine
Indications
- Convert hemodynamically stable narrow complex regular tachycardia with a pulse
Albuterol Sulfate
Indications
- Treatment of bronchospasm
- Treatment of hyperkalemia
Amiodarone
Indications
- V Fib
- Pulseless V Tach
- Reg wide complex tachycardia w/ pulse
- Irreg wide complex tachycardia
Aspirin
Indications
- Cardiac chest pain
- Suspected acute coronary syndrome
Adenosine
Contraindications
- 2nd or 3rd degree heart block
- Poison or drug induced tachycardia
- Known hypersensitivity
- Allergy
Albuterol Sulfate
Contraindications
- Allergy
Amiodarone
Contraindications
- 2nd or 3rd degree AV blocks
- Allergy
Aspirin
Contraindications
- Active GI bleed
- 324mg taken in pst 24 hours
- Allergy
Adenosine
Precautions and Side Effects
- May cause brief asystole, facial flushing, dizziness, headache, nausea and transient shortness of breath
- IV/IO adenosine has been shown to produce bronchospasm in asthmatic pts
- If pt becomes hemodynamically unstable, cardioversion should occur
Albuterol Sulfate
Precautions and Side Effects
- May cause dizziness, headache, anxiety, palpitations, sweating and muscle tremors
- Clinically significant arrhythmias may occur in pts with underlying cardiac disorders
- Relative contraindication include symptomatic tachycardia, tachyarrythmias and anginal chest pain
Amiodarone
Precautions and Side Effects
- May cause hypotension and bradycardia
Aspirin
Precautions and Side Effects
- May cause GI discomfort and nausea
- May cause wheezing
Adenosine
Administration
Route: IV/IO
Onset: 20-30 sec
Peak Effect: 20-30 sec
Duration: 30 sec
Albuterol Sulfate
Administration
Route: SVN
Onset: 5-15 mins
Peak Effect: 1-1.5 hrs
Duration: 3-6 hrs
Amiodarone
Administration
Route: IV/IO
Onset: 1-2 mins
Peak Effect: 10 mins
Duration: variable
Apirin
Administration
Route: PO
Onset: 5-30 mins
Peak Effect: 1-2 hours
Duration: 4-6 hours
