Week 3 - Digestion and Excretion systems Flashcards
Function of the digestive tract?
What’s its other name?
Ingestion and chemical as well as mechanical digestion
Also called alimentary canal
True or false? Dentition evolved with animals as food sources changed
true
mastication?
chewing of food
What’s the Buccal cavity? What does it contain?
Space between the jaws.
Contains: teeth, tongue, salivary glands and more
What does saliva contain and how does it aid digestion?
Salivary amylase - breaks down starch into disaccharide maltose.
What’s the epiglottis? What does it do?
Flap of cartilage that prevents the bolus entering trachea instead of oesophogus - so prevents choking.
What’s the bolus?
mix of saliva and food being digested
What does the oesophagus contain? And why?
Two layers of smooth muscle
This muscle moves bolus along as peristalsis
What’s the process of the bolus moving along the oesophagus?
Peristalsis
Main functions of the stomach?
- Storage of injested food
- Mechanical breakdown of injested food
- Chemical breakdown of injested food by enzymes and other chemicals secreted in gastric juice.
Why is the stomach wall highly folded?
Larger surface area
What does the stomach contains in a lot of the pits of it’s wall?
Gastric glands
What are the components of stomach’s gastric juice?
Mucus, hydrochloric acid and pepsinogen
What are the three cell types in the stomach wall and what do they secrete?
Goblet cells - Mucus
Parietral cells - Hydrochloric acid
Chief cells - Pepsinogen
After what is bolus referred to as Acid chyme?
After chemical and mechanical digestion
How does acid chyme leave the stomach?
Though the pyloric sphincter into the small intestine.
How is digestion able to occur in a highly acidic stomach?
- Inactive Zymogen: Pepsinogen has a masking sequence that prevents it binding to substrates and reacting.
- But in low PH this triggers masking sequence to come off of active site therefore exposing the active site.
- Its now called the active enzyme: pepsin. Which reacts to acid digestion in low PH. In this case 1-2 PH.
What does the pancreas have that allows it to regulate blood glucose levels?
a-cells secrete glucogen
B-cells secrete insulin
What is homeostasis?
Normal blood glucose level (state of homeostasis)
Steps for blood glucose regulation, when it’s too high?
- Rising blood glucose level
- High level detected by insulin secreting B-cell of pancreas.
- Stimulated to release more insulin into blood stream
- So body cells take up more glucose and the liver takes up excess glucose and stores it as glycogen.
- Blood glucose declines to set point, stimulation for insulin secretion stops, body returns to state of homeostasis.
Steps for blood glucose regulation, when it’s too low?
- Declining blood glucose level
- Detected by glucagon releasing a-cells of pancreas.
- Stimulated to release glucagon into blood stream to get to the liver.
- Glucagon at the liver converts stored glycogen back into glucose
- Glucose is released back into blood
Glucose level rises to a set point, stimulus for glucagon release stops and body returns to state of homeostasis.
Main components of pancreatic juice?
Bile salts, pancreatic amylase, lipase, maltase, lactase, mucus and water.
How many litres of pancreatic juice produced daily?
2 litres
What does the gall bladder serve as?
Reservoir for bile which contains pigment: bilirubin.
What are gallstones?
Deposits that form in the gall bladder. Usually occur from high cholesterol diet. Can block ducts requiring surgery.
Features of the liver?
- Self-regenerating
- Secretes bile - which emulsifies fats during digestion
Compromised of lobules (Segments of tissue)
Roles of liver?
- Stores iron, vitamin A and D
- Destroying old red blood cells
- Produces plasma proteins
- Breaks down poisons (detoxification)
- Carbohydrate metabolism (blood glucose control and storage of glycogen